Evidence map›Paper›PMID 35064111›Full record

ArticleNature communications2022

Multicomponent double Mannich alkylamination involving C(sp

Zhencheng Lai, Rongkai Wu, Jiaming Li, Xing Chen, Linwei Zeng, Xi Wang, Jingjing Guo, Zujin Zhao, Hironao Sajiki, Sunliang Cui

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhencheng Lai *Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China.
Rongkai Wu *Department of Chemistry, Zhejiang University, 38 Zheda Road, Hangzhou, 310027, China.
Jiaming Li *Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China.
Xing ChenInstitute of Molecular Plus, Tianjin University, Tianjin, 300072, China.
Linwei ZengInstitute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China.
Xi WangSchool of Science, Beijing Jiaotong University, Beijing, 100044, China.
Jingjing GuoState Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, 510640, China.
Zujin ZhaoState Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, 510640, China.ORCID http://orcid.org/0000-0002-0618-6024
Hironao SajikiLaboratory of Organic Chemistry, Gifu-Pharmaceutical University, Gifu, 501-1196, Japan.ORCID http://orcid.org/0000-0003-2792-6826
Sunliang CuiInstitute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China. slcui@zju.edu.cn.ORCID http://orcid.org/0000-0001-9407-5190

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alkylamines are ubiquitous in pharmaceuticals, materials and agrochemicals. The Mannich reaction is a well-known three-component reaction for preparing alkylamines and has been widely used in academic research and industry. However, the nucleophilic components in this process rely on C(sp

Identifiers

PMID35064111
PMCPMC8782832

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.