Evidence map›Paper›PMID 35064056›Full record

Observational studyOpen heart2022

Occurrence and predictors of pericardial effusion requiring invasive treatment following heart valve surgery.

Britt Borregaard, Kirstine Lærum Sibilitz, Marc Gjern Weiss, Ola Ekholm, Emilie Karense Lykking, Stine Nørris Nielsen, Lars Peter Riber, Jordi Sanchez Dahl, Jacob Eifer Moller

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Open heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Cardiac tamponade.Nature reviews. Disease primers · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Britt BorregaardDepartment of Cardiology, Odense Universitetshospital, Odense, Denmark Britt.Borregaard@rsyd.dk.ORCID 0000-0003-2702-0231
Kirstine Lærum SibilitzDepartment of Cardiology, Copenhagen University Hospital, Copenhagen, Denmark.ORCID 0000-0002-3387-7971
Marc Gjern WeissDepartment of Cardiac, Thoracic and Vascular Surgery, Odense Universitetshospital, Odense, Denmark.
Ola EkholmNational Institute of Public Health, University of Southern Denmark, Odense, Denmark.
Emilie Karense LykkingDepartment of Cardiac, Thoracic and Vascular Surgery, Odense Universitetshospital, Odense, Denmark.
Stine Nørris NielsenDepartment of Cardiology, Odense Universitetshospital, Odense, Denmark.
Lars Peter RiberDepartment of Cardiac, Thoracic and Vascular Surgery, Odense Universitetshospital, Odense, Denmark.
Jordi Sanchez DahlDepartment of Cardiology, Odense Universitetshospital, Odense, Denmark.
Jacob Eifer MollerDepartment of Cardiology, Odense Universitetshospital, Odense, Denmark.
University of Southern Denmark · DKAarhus University · DKCopenhagen University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the occurrence of significant pericardial effusion, and to investigate characteristics associated with pericardial effusion within three months following heart valve surgery.

methodsA retrospective, observational cohort study including adult patients undergoing heart valve surgery at Odense University Hospital from August 2013 to November 2017. Data were gathered from The Western Denmark Heart Registry and electronic patient records.Cox proportional hazard models were used to investigate the associations between characteristics associated with significant pericardial effusion during index admission and within 3 months. Results are presented as HR with 95% CI.

resultsIn total, 1460 patients were included (70% men, median age 71 years (IQR 63-76)) and of those, n=230 patients (16%) developed significant pericardial effusion.EuroScore II was significantly associated with an increased risk of pericardial effusion during index admission and associated with a lower risk following discharge (index admission HR 1.05, 95% CI 1.02 to 1.08, after discharge HR 0.80, 95% CI 0.69 to 0.92). Increasing age (HR 0.97, 95% CI 0.95 to 0.98 per year) and concomitant coronary artery bypass grafting versus isolated valve surgery (HR 0.58, 95% CI 0.35 to 0.97) were significantly associated with a reduced risk of pericardial effusions in both periods. Being a man (HR 2.30, 95% CI 1.32 to 4.01) and aortic valve disease versus mitral valve disease (HR 2.16, 95% CI 1.20 to 3.90) were significantly associated with an increased risk after discharge.

conclusionSignificant pericardial effusions requiring drainage were present in 16% of cases following heart valve surgery, and different clinical characteristics were associated with the development of effusion.

Indexed as

AgedCardiac Surgical ProceduresDenmarkEchocardiographyFemaleFollow-Up StudiesHeart Valve DiseasesHumansIncidenceMaleMiddle AgedPericardial EffusionPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk Factorscardiac surgical proceduresheart valve diseasespericardial effusion

Identifiers

PMID35064056
PMCPMC8785202
OpenAlexW4207005801

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.