Evidence map›Paper›PMID 35064012›Full record

ArticleEmergency medicine journal : EMJ2022

Feasibility of prehospital identification of non-ST-elevation myocardial infarction by ECG, troponin and echocardiography.

Lars Jacobsen, Bjørnar Grenne, Roy Bjørkholt Olsen, Jarle Jortveit

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Emergency medicine journal : EMJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04223986 (Prehospital Risk Stratification in Acute Coronary Syndromes- Feasibility Trial), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04223986 nacompletednot on this map

Prehospital Risk Stratification in Acute Coronary Syndromes- Feasibility Trial

TypeinterventionalSponsorSorlandet Hospital HFRan2017 to 2018Enrolled126ConditionsAcute Coronary Syndrome, Non-ST Elevation Myocardial Infarction (nSTEMI)ArmsUltrasound, Troponin- T quick test
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Diagnostic and prognostic value of regional wall motion abnormalities in patients with non-ST-elevation myocardial infarction.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  4. Article
  5. How Close Are We to Patient-Side Troponin Testing?Journal of clinical medicine · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lars JacobsenNorwegian Air Ambulance Foundation, Oslo, Norway.ORCID http://orcid.org/0000-0002-8602-9618
Bjørnar GrenneClinic of Cardiology, St. Olavs Hospital, Trondheim, Norway.ORCID http://orcid.org/0000-0002-2984-6865
Roy Bjørkholt OlsenDepartment of Anesthesiology, Sorlandet Hospital Arendal, Arendal, Norway.
Jarle JortveitDepartment of Cardiology, Sorlandet Hospital Arendal, Arendal, Norway jarle.jortveit@sshf.no.ORCID http://orcid.org/0000-0003-0524-9852
Sørlandet Hospital Arendal · NONorwegian University of Science and Technology · NOStiftelsen Norsk Luftambulanse · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrehospital identification and selection of treatment strategy in patients with suspected non-ST-elevation myocardial infarction (NSTEMI) is challenging. The aim of this study was to evaluate the feasibility and diagnostic accuracy of prehospital ECG, troponin T (TnT) and transthoracic echocardiography (TTE) acquired by paramedics in early identification of NSTEMI.

methodsConsecutive patients requesting an ambulance from Sorlandet Hospital, Norway due to chest pain between November 2017 and January 2020 were screened for inclusion in the study. One ambulance was equipped with ECG recorder, point-of-care TnT test and TTE scanner, and six paramedics were given necessary training. ECG, TnT result and TTE images were acquired prehospitally and transferred to an in-hospital cardiologist. NSTEMI was suspected in patients with ischaemic ECG changes, elevated TnT or myocardial regional wall motion abnormalities (RWMA) at TTE.

resultsA total of 253 patients were included in the study. ECG was interpretable by cardiologists in 243 (96%), TnT in 238 (94%) and TTE images in 240 (95%) patients. NSTEMI was the discharge diagnosis in 22 (9%) of these patients. Four (18%) patients with NSTEMI had ischaemic ECG changes, elevated TnT and RWMA at TTE. Eight (36%) patients with NSTEMI had positive findings at two of the diagnostic methods, six (27%) patients had positive findings at one, and four (18%) patients had no positive findings in any of the diagnostic methods. In three patients (14%) with NSTEMI, RWMA was the only positive test. The negative and positive predictive values for RWMA were 42% and 96%, respectively.

conclusionsPrehospital acquisition of ECG, TnT and interpretable TTE images by paramedics were feasible in most patients with chest pain. Based on these examinations, it was possible to identify the majority of cases with NSTEMI prehospitally and admit the patients directly to a hospital with facilities for percutaneous coronary intervention (PCI) for further treatment. TRIAL REGISTRATION NUMBER: NCT04223986.

Indexed as

Non-ST Elevated Myocardial InfarctionPercutaneous Coronary InterventionAmbulancesChest PainEchocardiographyElectrocardiographyFeasibility StudiesHumansTroponinTroponin TTroponinTroponin Tacute myocardial infarct

Identifiers

PMID35064012
PMCPMC9411895
OpenAlexW4206537727

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.