Evidence map›Paper›PMID 35063447›Full record

ArticleChest2022

Different Cytokine Patterns in BMPR2-Mutation-Positive Patients and Patients With Pulmonary Arterial Hypertension Without Mutations and Their Influence on Survival.

Max Schwiening, Emilia M Swietlik, Divya Pandya, Keith Burling, Peter Barker, Oliver Y Feng, Carmen M Treacy, Susana Abreu, S John Wort, Joanna Pepke-Zaba and 4 more

Abstract read
In one paragraph

Article in Chest, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Interleukin-6 is critical in the development of pulmonary vascular disease inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Max SchwieningCambridge Institute for Medical Research, University of Cambridge, Cambridge, England.
Emilia M SwietlikDepartment of Respiratory Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England; Royal Papworth Hospital NHS Foundation Trust, Papworth Road, Trumpington, Cambridge, England.
Divya PandyaDepartment of Respiratory Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England.
Keith BurlingNIHR Cambridge BRC Core Biochemical Assay Laboratory (CBAL), Cambridge University Hospitals NHS Foundation Trust, Cambridge, England.
Peter BarkerNIHR Cambridge BRC Core Biochemical Assay Laboratory (CBAL), Cambridge University Hospitals NHS Foundation Trust, Cambridge, England.
Oliver Y FengStatistical Laboratory, Centre for Mathematical Sciences, Cambridge, England.
Carmen M TreacyDepartment of Respiratory Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England.
Susana AbreuCambridge Institute for Medical Research, University of Cambridge, Cambridge, England.
S John WortNational Heart and Lung Institute, Imperial College London, London, England.
Joanna Pepke-ZabaRoyal Papworth Hospital NHS Foundation Trust, Papworth Road, Trumpington, Cambridge, England.
Stefan GrafDepartment of Respiratory Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England; Department of Hematology, University of Cambridge, Cambridge, England; NIHR BioResource for Translational Research, Cambridge Biomedical Campus, Cambridge, England.
Stefan J MarciniakCambridge Institute for Medical Research, University of Cambridge, Cambridge, England; Royal Papworth Hospital NHS Foundation Trust, Papworth Road, Trumpington, Cambridge, England.
Nicholas W MorrellDepartment of Respiratory Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England.
Elaine SoonCambridge Institute for Medical Research, University of Cambridge, Cambridge, England; Department of Respiratory Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England. Electronic address: eels2@cam.ac.uk.

Funding

British Heart Foundation CH/09/001/25945British Heart Foundation RE/18/1/34212British Heart Foundation RG/13/4/30107British Heart Foundation SP/12/12/29836British Heart Foundation SP/18/10/33975Medical Research Council G0802261Medical Research Council G1002610Medical Research Council MR/K020919/1Medical Research Council MR/R008051/1Medical Research Council MR/R009120/1Medical Research Council MR/V028669/1Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pulmonary Arterial HypertensionBone Morphogenetic Protein Receptors, Type IICytokinesFamilial Primary Pulmonary HypertensionHumansMutationBMPR2 protein, humanBone Morphogenetic Protein Receptors, Type IICytokines

Identifiers

PMID35063447
PMCPMC9248075

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.