Evidence map›Paper›PMID 35062897›Full record

ArticleBMC ophthalmology2022

Epstein-Barr viral corneal stromal keratitis occurring during rheumatoid arthritis treatment: a case report.

Kazuya Yamashita, Rio Sato, Ryuki Fukumoto, Yoshiko Ofuji, Takashi Nagamoto, Hirohisa Kubono, Mari Kawamura, Kotaro Suzuki

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kazuya YamashitaDepartment of Ophthalmology, Keiyu Hospital, 3-7-3 Minatomirai, Yokohama Nishi-ku, Kanagawa, 220-8521, Japan. kazuyamashita@keio.jp.ORCID http://orcid.org/0000-0001-8517-8227
Rio SatoDepartment of Ophthalmology, Keiyu Hospital, 3-7-3 Minatomirai, Yokohama Nishi-ku, Kanagawa, 220-8521, Japan.
Ryuki FukumotoDepartment of Ophthalmology, Keiyu Hospital, 3-7-3 Minatomirai, Yokohama Nishi-ku, Kanagawa, 220-8521, Japan.
Yoshiko OfujiDepartment of Ophthalmology, Keiyu Hospital, 3-7-3 Minatomirai, Yokohama Nishi-ku, Kanagawa, 220-8521, Japan.
Takashi NagamotoDepartment of Ophthalmology, Keiyu Hospital, 3-7-3 Minatomirai, Yokohama Nishi-ku, Kanagawa, 220-8521, Japan.
Hirohisa KubonoDepartment of Ophthalmology, Keiyu Hospital, 3-7-3 Minatomirai, Yokohama Nishi-ku, Kanagawa, 220-8521, Japan.
Mari KawamuraDepartment of Ophthalmology, Keiyu Hospital, 3-7-3 Minatomirai, Yokohama Nishi-ku, Kanagawa, 220-8521, Japan.
Kotaro SuzukiDepartment of Ophthalmology, Keiyu Hospital, 3-7-3 Minatomirai, Yokohama Nishi-ku, Kanagawa, 220-8521, Japan.
keiyu Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA case of Epstein-Barr viral (EBV) corneal stromal keratitis during rheumatoid arthritis (RA) treatment is presented. CASE PRESENTATION: A 74-year-old female undergoing RA treatment was previously treated for bacterial corneal ulcer and herpetic keratitis and healed with antibiotic eye drops and topical anti-herpes ointment. At the first visit to our hospital, she presented with findings of monocular posterior interstitial keratitis with neovascularization mostly located in the inferior cornea with a corneal epithelial defect. The right eye showed no thinning of the corneal periphery and anterior uveitis. Her RA had subsided with oral steroid treatment, and infectious mononucleosis (IM) had not developed. EBV DNA could be detected in her corneal sample. After an extended but ineffective period to antibiotic treatment the corneal infiltrate responded rapidly to topical corticosteroids.

conclusionEBV can cause stromal keratitis without IM during treatment for RA.

Indexed as

Arthritis, RheumatoidCorneal UlcerKeratitis, HerpeticAgedCorneaFemaleHerpesvirus 4, HumanHumansEpstein-Barr virusMultiplex polymerase chain reactionRheumatoid arthritisStromal keratitisUveitis

Identifiers

PMID35062897
PMCPMC8781591
OpenAlexW4206161705

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.