Evidence map›Paper›PMID 35062679›Full record

ArticleVaccines2021

SARS-CoV-2 Post Vaccinated Adverse Effects and Efficacy in the Egyptian Population.

Marwa O Elgendy, Ahmed O El-Gendy, Abdulaziz Ibrahim Alzarea, Sarah Mahmoud, Saad S Alqahtani, Alzhraa M Fahmy, Hesham R El-Seedi, Ahmed M Sayed, Ahmed D Alatawi, Mohamed E A Abdelrahim and 1 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Marwa O ElgendyDepartment of Clinical Pharmacy, Teaching Hospital of Faculty of Medicine, Beni-Suef University, Beni-Suef 62513, Egypt.ORCID 0000-0002-5466-0552
Ahmed O El-GendyDepartment of Microbiology and Immunology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62513, Egypt.ORCID 0000-0002-0980-5185
Abdulaziz Ibrahim AlzareaClinical Pharmacy Department, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0003-0604-6299
Sarah MahmoudDepartment of Clinical and Chemical Pathology, Faculty of Medicine, Beni-Suef University, Beni-Suef 62513, Egypt.
Saad S AlqahtaniDepartment of Clinical Pharmacy, Collage of Pharmacy, Jazan University, Jazan 82511, Saudi Arabia.
Alzhraa M FahmyTropical Medicine and Infectious Diseases Department, Faculty of Medicine, Beni-Suef University, Beni-Suef 62513, Egypt.
Hesham R El-SeediPharmacognosy Group, Department of Pharmaceutical Biosciences, BMC, Uppsala University, SE 751 24 Uppsala, Sweden.
Ahmed M SayedDepartment of Pharmacognosy, Faculty of Pharmacy, Nahda University, Beni-Suef 62513, Egypt.ORCID 0000-0002-1442-183X
Ahmed D AlatawiClinical Pharmacy Department, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.
Mohamed E A AbdelrahimClinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62513, Egypt.ORCID 0000-0003-0227-8404
Abdullah S AlanaziClinical Pharmacy Department, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0002-8120-4018
Beni-Suef University · EGJouf University · SAJazan University · SAJiangsu University · CNNahda University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccines are the solution to overcome SARS-CoV-2. This study aimed to determine the post-Sinopharm vaccine safety-profile and immunity through antibody titers. Data were collected using a structured questionnaire from Egyptian participants who received two doses of Sinopharm vaccine. Data were divided into three parts, the first and second parts were to detect participants' post-first and second dose symptoms and practices, and the third for the results of IgG anti spike protein antibodies test and laboratory tests. Pain, redness, swelling at the injection site, headache, fatigue, and lethargy were the most common post-vaccine symptoms for both first and second doses. Most of the participants felt mild or no symptoms after vaccination. The symptoms started mostly during the first day post-vaccination and lasted for no more than two days. Forty-nine percent of the participants resulted in positive antibodies tests on day 18 post-vaccination. The average antibody level for vaccinated participants with past SARS-CoV-2 infection was much higher than that for non-past infected participants. These vaccines' administration methods need to be reevaluated by changing the dose, dose interval, adding a third dose, or mixing it with other vaccines with different techniques to improve their protection rates. Further studies are required to validate this finding.

Indexed as

adverse effectsanti-spikeCOVID-19IgGSARS-CoV-2Sinopharm vaccine

Identifiers

PMID35062679
PMCPMC8779046
OpenAlexW4205984387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.