Evidence map›Paper›PMID 35062675›Full record

ArticleVaccines2021

Eosinophilic Granulomatosis with Polyangiitis Relapse after COVID-19 Vaccination: A Case Report.

Giulia Costanzo, Andrea Giovanni Ledda, Alessandra Ghisu, Matteo Vacca, Davide Firinu, Stefano Del Giacco

Open access · goldAbstract readCase Reports
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Eosinophil-associated disease after SARS-CoV-2 infection or vaccination: EGPA and related entities.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Giulia CostanzoDepartment of Medical Sciences and Public Health, University of Cagliari, 09131 Cagliari, Italy.ORCID 0000-0003-2269-0439
Andrea Giovanni LeddaDepartment of Medical Sciences and Public Health, University of Cagliari, 09131 Cagliari, Italy.
Alessandra GhisuDepartment of Medical Sciences and Public Health, University of Cagliari, 09131 Cagliari, Italy.
Matteo VaccaDepartment of Medical Sciences and Public Health, University of Cagliari, 09131 Cagliari, Italy.
Davide FirinuDepartment of Medical Sciences and Public Health, University of Cagliari, 09131 Cagliari, Italy.ORCID 0000-0002-5768-391X
Stefano Del GiaccoDepartment of Medical Sciences and Public Health, University of Cagliari, 09131 Cagliari, Italy.ORCID 0000-0002-4517-1749
University of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe here describe the case of a 71-year-old Caucasian woman previously diagnosed with Eosinophilic Granulomatosis with Polyangiitis (EGPA) that had been treated with Mepolizumab, an anti-IL5 monoclonal antibody, since 2019 with a good clinical response.

methodsShe had a mild COVID-19 in December 2020 and she tested negative for SARS-CoV-2 infection in only late January 2021. In April 2021 she received the first dose of mRNA BNT162b2 vaccine. Ten days later she developed myalgia, dyspnea and numbness of the limbs due to a relapse of EGPA that occurred during Mepolizumab treatment.

Indexed as

COVID-19EGPAmRNA BNT162b2 vaccinerelapsevaccine

Identifiers

PMID35062675
PMCPMC8779858
OpenAlexW4200274922

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.