Evidence map›Paper›PMID 35062663›Full record

ArticleVaccines2021

Expression of SARS-CoV-2 Spike Protein Receptor Binding Domain on Recombinant

Johnny Chun-Chau Sung, Ying Liu, Kam-Chau Wu, Man-Chung Choi, Chloe Ho-Yi Ma, Jayman Lin, Emily Isabel Cheng He, David Yiu-Ming Leung, Eric Tung-Po Sze, Yusuf Khwaja Hamied and 2 more

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Recent development of oral vaccines (Review).Experimental and therapeutic medicine · 2024
    Review
  4. Computational and structural biotechnology journal · 2023
    Article
  5. Article
  6. An Algae-Made RBD from SARS-CoV-2 Is Immunogenic in Mice.Pharmaceuticals (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Johnny Chun-Chau SungResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
Ying LiuResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
Kam-Chau WuResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
Man-Chung ChoiResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
Chloe Ho-Yi MaResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
Jayman LinResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
Emily Isabel Cheng HeResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
David Yiu-Ming LeungZentrogene Bioscience Laboratory Limited, Hong Kong, China.
Eric Tung-Po SzeSchool of Science and Technology, Hong Kong Metropolitan University, Hong Kong, China.ORCID 0000-0001-6197-0893
Yusuf Khwaja HamiedCipla Limited, Mumbai 400013, India.
Dominic Man-Kit LamL&L Immunotherapy Company Limited, Hong Kong, China.
Keith Wai-Yeung KwongResearch Department, DreamTec Cytokines Limited, Hong Kong, China.ORCID 0000-0001-5229-0124
Cipla (India) · INSichuan University · CN

Funding

Hong Kong Research Grants Council UGC/IDS(R)16/19Innovation and Technology Commission PRP/008/21FX
6 · The paper itself

Abstract

Various types of vaccines, such as mRNA, adenovirus, and inactivated virus by injection, have been developed to prevent SARS-CoV-2 infection. Although some of them have already been approved under the COVID-19 pandemic, various drawbacks, including severe side effects and the requirement for sub-zero temperature storage, may hinder their applications.

Indexed as

Bacillus subtilisCOVID-19oral vaccineSARS-CoV-2spike proteinsporulation

Identifiers

PMID35062663
PMCPMC8780001
OpenAlexW4200497835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.