Evidence map›Paper›PMID 35062358›Full record

ReviewViruses2022

Review of Oral Rabies Vaccination of Dogs and Its Application in India.

Gowri Yale, Marwin Lopes, Shrikrishna Isloor, Jennifer R Head, Stella Mazeri, Luke Gamble, Kinzang Dukpa, Gyanendra Gongal, Andrew D Gibson

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Rabies post-exposure prophylaxis in India: a SWOT analysis.Therapeutic advances in vaccines and immunotherapy · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Optimising rabies vaccination of dogs in India.Epidemiology and infection · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Oral Vaccination of Dogs in India as a Strategy for Elimination of Rabies: Scope of Implementation.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Gowri YaleMission Rabies, Panjim 403002, India.ORCID 0000-0002-8953-7167
Marwin LopesDepartment of Animal Husbandry & Veterinary Services, Government of Goa, Panjim 403001, India.
Shrikrishna IsloorBangalore Veterinary College, Hebbal, Bengaluru 560024, Karnataka, India.
Jennifer R HeadDivision of Epidemiology, University of California Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0003-1449-4171
Stella MazeriThe Roslin Institute, The Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Veterinary Centre, Midlothian, Roslin EH25 9RG, UK.ORCID 0000-0002-4591-8267
Luke GambleMission Rabies, Dorset, Cranborne BH21 5PZ, UK.
Kinzang DukpaWorld Organisation for Animal Health (OIE), Regional Representation for Asia and the Pacific, Tokyo 113-8657, Japan.
Gyanendra GongalWorld Health Organization (WHO), Regional Office for South East Asia, New Delhi 110002, India.ORCID 0000-0002-6539-7569
Andrew D GibsonThe Roslin Institute, The Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Veterinary Centre, Midlothian, Roslin EH25 9RG, UK.ORCID 0000-0002-4641-2583
Roslin Institute · GBAnimal Husbandry & Veterinary · INOrganisation Mondiale de la Santé Animale · FRRamakrishna Mission Vidyamandira · INUniversity of California, Berkeley · USWorld Health Organization Regional Office for South-East Asia · IN

Funding

World Health Organization 001
6 · The paper itself

Abstract

Oral rabies vaccines (ORVs) have been in use to successfully control rabies in wildlife since 1978 across Europe and the USA. This review focuses on the potential and need for the use of ORVs in free-roaming dogs to control dog-transmitted rabies in India. Iterative work to improve ORVs over the past four decades has resulted in vaccines that have high safety profiles whilst generating a consistent protective immune response to the rabies virus. The available evidence for safety and efficacy of modern ORVs in dogs and the broad and outspoken support from prominent global public health institutions for their use provides confidence to national authorities considering their use in rabies-endemic regions. India is estimated to have the largest rabies burden of any country and, whilst considerable progress has been made to increase access to human rabies prophylaxis, examples of high-output mass dog vaccination campaigns to eliminate the virus at the source remain limited. Efficiently accessing a large proportion of the dog population through parenteral methods is a considerable challenge due to the large, evasive stray dog population in many settings. Existing parenteral approaches require large skilled dog-catching teams to reach these dogs, which present financial, operational and logistical limitations to achieve 70% dog vaccination coverage in urban settings in a short duration. ORV presents the potential to accelerate the development of approaches to eliminate rabies across large areas of the South Asia region. Here we review the use of ORVs in wildlife and dogs, with specific consideration of the India setting. We also present the results of a risk analysis for a hypothetical campaign using ORV for the vaccination of dogs in an Indian state.

Indexed as

Administration, OralAnimalsAnimals, WildAntibodies, ViralDog DiseasesDogsIndiaMass VaccinationRabiesRabies VaccinesRabies virusVaccinationAntibodies, ViralRabies Vaccinescanine rabies controldog mediated human rabiesfree roaming dogsoral rabies vaccine

Identifiers

PMID35062358
PMCPMC8777998
OpenAlexW4205207247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.