Evidence map›Paper›PMID 35062297›Full record

ArticleViruses2022

Serological Positivity against Selected

Daniel Felipe Barrantes Murillo, Marta Piche-Ovares, José Carlos Gamboa-Solano, Luis Mario Romero, Claudio Soto-Garita, Alejandro Alfaro-Alarcón, Eugenia Corrales-Aguilar

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Daniel Felipe Barrantes MurilloPathology Department, Universidad Nacional Costa Rica, Heredia 40104, Costa Rica.
Marta Piche-OvaresVirology-CIET (Research Center for Tropical Diseases), Faculty of Microbiology, University of Costa Rica, San Jose 11501, Costa Rica.ORCID 0000-0003-4809-0095
José Carlos Gamboa-SolanoVirology-CIET (Research Center for Tropical Diseases), Faculty of Microbiology, University of Costa Rica, San Jose 11501, Costa Rica.
Luis Mario RomeroPathology Department, Universidad Nacional Costa Rica, Heredia 40104, Costa Rica.ORCID 0000-0002-6498-2061
Claudio Soto-GaritaVirology-CIET (Research Center for Tropical Diseases), Faculty of Microbiology, University of Costa Rica, San Jose 11501, Costa Rica.
Alejandro Alfaro-AlarcónPathology Department, Universidad Nacional Costa Rica, Heredia 40104, Costa Rica.ORCID 0000-0001-9481-6606
Eugenia Corrales-AguilarVirology-CIET (Research Center for Tropical Diseases), Faculty of Microbiology, University of Costa Rica, San Jose 11501, Costa Rica.ORCID 0000-0002-0845-8329
Universidad Nacional · CRUniversidad de Costa Rica · CR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arboviruses have two ecological transmission cycles: sylvatic and urban. For some, the sylvatic cycle has not been thoroughly described in America. To study the role of wildlife in a putative sylvatic cycle, we sampled free-ranging bats and birds in two arbovirus endemic locations and analyzed them using molecular, serological, and histological methods. No current infection was detected, and no significant arbovirus-associated histological changes were observed. Neutralizing antibodies were detected against selected arboviruses. In bats, positivity in 34.95% for DENV-1, 16.26% for DENV-2, 5.69% for DENV-3, 4.87% for DENV-4, 2.43% for WNV, 4.87% for SLEV, 0.81% for YFV, 7.31% for EEEV, and 0.81% for VEEV was found. Antibodies against ZIKV were not detected. In birds, PRNT results were positive against WNV in 0.80%, SLEV in 5.64%, EEEV in 8.4%, and VEEV in 5.63%. An additional retrospective PRNT analysis was performed using bat samples from three additional DENV endemic sites resulting in a 3.27% prevalence for WNV and 1.63% for SLEV. Interestingly, one sample resulted unequivocally WNV positive confirmed by serum titration. These results suggest that free-ranging bats and birds are exposed to not currently reported hyperendemic-human infecting

Indexed as

Seroepidemiologic StudiesAlphavirusAlphavirus InfectionsAnimalsAnimals, WildAntibodies, NeutralizingAntibodies, ViralBird DiseasesBirdsChiropteraCosta RicaDengue VirusDisease ReservoirsFemaleFlavivirusFlavivirus InfectionsAntibodies, NeutralizingAntibodies, ViralarbovirusbatsbirdsCosta Ricawildlife

Identifiers

PMID35062297
PMCPMC8780000
OpenAlexW4205685724

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.