Evidence map›Paper›PMID 35062281›Full record

ArticleViruses2022

Intra-Host SARS-CoV-2 Evolution in the Gut of Mucosally-Infected

Lori A Rowe, Brandon J Beddingfield, Kelly Goff, Stephanie Z Killeen, Nicole R Chirichella, Alexandra Melton, Chad J Roy, Nicholas J Maness

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lori A RoweTulane National Primate Research Center, Covington, LA 70433, USA.ORCID 0000-0003-3744-496X
Brandon J BeddingfieldTulane National Primate Research Center, Covington, LA 70433, USA.ORCID 0000-0002-9438-1304
Kelly GoffTulane National Primate Research Center, Covington, LA 70433, USA.
Stephanie Z KilleenTulane National Primate Research Center, Covington, LA 70433, USA.
Nicole R ChirichellaTulane National Primate Research Center, Covington, LA 70433, USA.
Alexandra MeltonTulane National Primate Research Center, Covington, LA 70433, USA.
Chad J RoyTulane National Primate Research Center, Covington, LA 70433, USA.ORCID 0000-0002-1710-6974
Nicholas J ManessTulane National Primate Research Center, Covington, LA 70433, USA.ORCID 0000-0002-9332-7891
Tulane University · US

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
Reservoir modulation by Nef and anti-nef CTLR21AI150413 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI MANESS, NICHOLAS JAMES · 2020 to 2021
$468k
NIH HHS AI150413-01NIH HHS HHSN27220170033INIH HHS P51 OD011104NIH HHS P51 OD01110459NIH HHS P51OD01110459
6 · The paper itself

Abstract

In recent months, several SARS-CoV-2 variants have emerged that enhance transmissibility and escape host humoral immunity. Hence, the tracking of viral evolutionary trajectories is clearly of great importance. Little is known about SARS-CoV-2 evolution in nonhuman primate models used to test vaccines and therapies and to model human disease. Viral RNA was sequenced from rectal swabs from

Indexed as

AnimalsChlorocebus aethiopsCOVID-19Disease Models, AnimalEvolution, MolecularMutationPolyproteinsRectumRNA, ViralSARS-CoV-2Spike Glycoprotein, CoronavirusVero CellsViral ProteinsORF1ab polyprotein, SARS-CoV-2PolyproteinsRNA, ViralSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Viral ProteinsAfrican green monkey (Chlorocebus aethiops)evolutionSARS-CoV-2

Identifiers

PMID35062281
PMCPMC8777858
OpenAlexW4225540133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.