Evidence map›Paper›PMID 35062250›Full record

ArticleViruses2021

Expansion of CD56

José L Casado, Elisa Moraga, Pilar Vizcarra, Héctor Velasco, Adrián Martín-Hondarza, Johannes Haemmerle, Sandra Gómez, Carmen Quereda, Alejandro Vallejo

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

José L CasadoDepartment of Infectious Diseases, Ramón y Cajal Institute for Health Research (IRyCIS), University Hospital Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0002-7639-8591
Elisa MoragaDepartment of Infectious Diseases, Ramón y Cajal Institute for Health Research (IRyCIS), University Hospital Ramón y Cajal, 28034 Madrid, Spain.
Pilar VizcarraDepartment of Infectious Diseases, Ramón y Cajal Institute for Health Research (IRyCIS), University Hospital Ramón y Cajal, 28034 Madrid, Spain.
Héctor VelascoDepartment of Infectious Diseases, Ramón y Cajal Institute for Health Research (IRyCIS), University Hospital Ramón y Cajal, 28034 Madrid, Spain.
Adrián Martín-HondarzaDepartment of Infectious Diseases, Ramón y Cajal Institute for Health Research (IRyCIS), University Hospital Ramón y Cajal, 28034 Madrid, Spain.
Johannes HaemmerleDepartment of Prevention of Occupational Risks, University Hospital Ramón y Cajal, 28034 Madrid, Spain.
Sandra GómezDepartment of Infectious Diseases, Ramón y Cajal Institute for Health Research (IRyCIS), University Hospital Ramón y Cajal, 28034 Madrid, Spain.
Carmen QueredaDepartment of Infectious Diseases, Ramón y Cajal Institute for Health Research (IRyCIS), University Hospital Ramón y Cajal, 28034 Madrid, Spain.
Alejandro VallejoDepartment of Infectious Diseases, Ramón y Cajal Institute for Health Research (IRyCIS), University Hospital Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0001-5360-878X
Instituto Cajal · ESHospital Universitario Ramón y Cajal · ES

Funding

Instituto de Salud Carlos III COV20-01304
6 · The paper itself

Abstract

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) infection induces elevated levels of inflammatory cytokines, which are mainly produced by the innate response to the virus. The role of NK cells, which are potent producers of IFN-γ and cytotoxicity, has not been sufficiently studied in the setting of SARS-CoV-2 infection. We confirmed a different distribution of NK cell subsets in hospitalized COVID-19 patients despite their NK cell deficiency. The impairment of this innate defense is mainly focused on the cytotoxic capacity of the CD56

Indexed as

AgedCD56 AntigenCOVID-19FemaleGPI-Linked ProteinsHospitalizationHumansInflammationKiller Cells, NaturalLymphocyte SubsetsMaleMiddle AgedReceptors, IgGReceptors, KIRSARS-CoV-2CD56 AntigenFCGR3B protein, humanGPI-Linked ProteinsNCAM1 protein, humanReceptors, IgGReceptors, KIRCOVID-19KIR receptorsNK cell subsetsSARS-CoV-2

Identifiers

PMID35062250
PMCPMC8780522
OpenAlexW4200078494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.