Evidence map›Paper›PMID 35062220›Full record

ArticleViruses2021

The European Prevalence of Resistance Associated Substitutions among Direct Acting Antiviral Failures.

Stephanie Popping, Valeria Cento, Carole Seguin-Devaux, Charles A B Boucher, Adolfo de Salazar, Eva Heger, Orna Mor, Murat Sayan, Dominique Salmon-Ceron, Nina Weis and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Stephanie PoppingDepartment of Viroscience, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands.ORCID 0000-0002-8959-4671
Valeria CentoDepartment of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy.
Carole Seguin-DevauxDepartment of Infection and Immunity, Luxembourg Institute of Health, 4354 Esch sur Alzette, Luxembourg.ORCID 0000-0003-0636-5222
Charles A B BoucherDepartment of Viroscience, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands.
Adolfo de SalazarDepartment of Clinical Microbiology & Infectious Diseases, Instituto Bioanitario Ibs.Granada, Hospital Universitario San Cecilio, 18012 Granada, Spain.
Eva HegerUniversity Hospital Cologne, 50937 Cologne, Germany.
Orna MorCentral Virology Laboratory, Ministry of Health, Sheba Medical Center, Ramat-Gan 52621, Israel.ORCID 0000-0003-3207-4226
Murat SayanClinical Laboratory, Faculty of Medicine, Kocaeli University, Kocaeli 41380, Turkey.
Dominique Salmon-CeronAssistance Publique Hopitaux de Paris, University of Paris, 75004 Paris, France.
Nina WeisDepartment of Infectious Diseases, Copenhagen University Hospital Hvidovre, 2650 Hvidovre, Denmark.
Henrik B KrarupDepartment of Molecular Diagnostics, Aalborg University Hospital, 9100 Aalborg, Denmark.
Robert J de KnegtDepartment of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Oana SăndulescuNational Institute for Infectious Diseases "Prof. Dr. Matei Bals", 021105 Bucharest, Romania.ORCID 0000-0002-2586-4070
Vladimir ChulanovNational Medical Research Center of Phthisiopulmonology & Infectious Diseases, 620039 Moscow, Russia.ORCID 0000-0001-6303-9293
David A M C van de VijverDepartment of Viroscience, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands.
Federico GarcíaThe European Society for Translational Antiviral Research, 3584 CX Utrecht, The Netherlands.ORCID 0000-0001-7611-781X
Francesca Ceccherini-SilbersteinThe European Society for Translational Antiviral Research, 3584 CX Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationAntiviral AgentsDEAD-box RNA HelicasesDrug Resistance, ViralDrug Therapy, CombinationEuropeFemaleGenotypeHepacivirusHepatitis CHumansMaleMiddle AgedNucleoside-TriphosphataseRetreatmentRNA-Dependent RNA PolymeraseAntiviral AgentsDEAD-box RNA HelicasesNS3 protein, hepatitis C virusNS-5 protein, hepatitis C virusNucleoside-TriphosphataseRNA-Dependent RNA PolymeraseSerine EndopeptidasesViral Nonstructural ProteinsViral Proteasesdirect-acting antiviralseliminationhepatitis Cresistanceresistance associated substitutions

Identifiers

PMID35062220
PMCPMC8781716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.