ArticlePloS one2022
Agreement between upper and lower limb measures to identify older adults with low skeletal muscle strength, muscle mass and muscle quality.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- The prevalence and influencing factors of dynapenia among middle-aged and elderly individuals with knee osteoarthritis: a cross-sectional analysis.BMC musculoskeletal disorders · 2026Article
- "Muscle quality": rethinking an imprecise term.European geriatric medicine · 2026Review
- Diagnostic variability in sarcopenia and sarcopenic obesity among older adults: a clinical and public health challenge.Frontiers in nutrition · 2026Article
- Association Between Muscle Quality Assessed by the 5-Repetition Sit-to-Stand Test and Falls in Community-Dwelling Older Adults in Japan: A Cross-Sectional Study.Geriatrics (Basel, Switzerland) · 2025Article
- Age- and sex-related development of osteosarcopenia in the agingFrontiers in aging · 2025Article
- Performance of calf circumference in identifying sarcopenia in older patients with chronic low back pain: a retrospective cross-sectional study.BMC geriatrics · 2024Article
- Thigh muscle by CT images as a predictor of mortality in patients with newly diagnosed colorectal cancer.Scientific reports · 2024Article
- Effects of Exercise Training on Muscle Quality in Older Individuals: A Systematic Scoping Review with Meta-Analyses.Sports medicine - open · 2023Article
- Article
- Muscle Evaluation and Hospital-Associated Disability in Acute Hospitalized Older Adults.The journal of nutrition, health & aging · 2022Observational
- Effects of Physical Activity on Physical Fitness and Functional Ability in Older Adults.Gerontology & geriatric medicineArticle
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdentifying low skeletal muscle strength (SMS), skeletal muscle mass (SMM) and skeletal muscle quality (SMQ) is pivotal for diagnosing sarcopenia cases. Age-related declines in SMS, SMM, and SMQ are dissimilar between the upper (UL) and lower limbs (LL). Despite this, both UL and LL measures have been used to assess SMS, SMM and SMQ in older adults. However, it is not clear whether there is agreement between UL and LL measures to identify older adults with low SMS, SMM and SMQ.
objectiveTo investigate the agreement between UL and LL measures to identify older adults with low SMS, SMM and SMQ.
methodsParticipants (n = 385; 66.1 ± 5.1 years; 75,4% females) performed the handgrip strength test (HGS) and the 30-s chair stand test (CST) to assess UL- and LL-SMS, respectively. The SMM was assessed by dual-energy X-ray absorptiometry (DXA). The UL-SMQ was determined as: handgrip strength (kgf) ÷ arm SMM (kg). LL-SMQ was determined as: 30-s CST performance (repetitions) ÷ leg SMM (kg). Results below the 25th percentile stratified by sex and age group (60-69 and 70-80 years) were used to determine low SMS, SMM and SMQ. Cohen's kappa coefficient (κ) was used for the agreement analyses.
resultsThere was a slight and non-significant agreement between UL and LL measures to identify older adults with low SMS (κ = 0.046; 95% CI 0.093-0.185; p = 0.352). There was a moderate agreement to identify low SMM (κ = 0.473; 95% CI 0.371-0.574; p = 0.001) and a fair agreement to identify low SMQ (κ = 0.206; 95% CI 0.082 to 0.330; p = 0.005).
conclusionThe agreement between UL and LL measures to identify older adults with low SMS, SMM and SMQ is limited, which might generate different clinical interpretations for diagnosing sarcopenia cases.
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