Acceptance of COVID-19 vaccines among college students: a study of the attitudes, knowledge, and willingness of students to vaccinate.

Universities are considered high risk areas for COVID-19 outbreaks given the crowded environment of campuses with high mobility and limited space. As such, vaccination is considered an essential intervention that could greatly reduce the incidence and spread of this deadly infectious disease. However, the willingness of college students to receive the COVID-19 vaccine varies significantly. Therefore, a study on the acceptance of COVID-19 vaccines in college students that explores the attitudes, knowledge, willingness, and key factors influencing vaccination acceptance is of great significance to improve vaccine coverage and control the pandemic. A cross-sectional survey was conducted on students from three universities in China. Descriptive statistics, independent sample t tests/one-way ANOVA (normal distribution), Mann-Whitney U tests/Kruskal-Wallis H tests (skewness distribution) and multivariate linear regression were performed. As a result, a total of 3,256 students participated in the survey. Students' willingness to receive the COVID-19 vaccine was high (86%), and they had good knowledge of the vaccine (77.9%). However, they had a low-risk perception of COVID-19 and less positive attitudes toward vaccination (69.8%). The main influencing factors were sex, age, specialty, grades, living environment, spending level, traveling to risk areas, and family members' vaccination experiences. We believed that to increase vaccination coverage among college students, more attention should be paid for students majoring in Science and Engineering, male students, those in the lower age group, students with low or very high economic levels, living in remote or rural areas, and family members having not received the COVID-19 vaccine.