ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2022
Membrane damage as mechanism of photodynamic inactivation using Methylene blue and TMPyP in Escherichia coli and Staphylococcus aureus.
Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 42 citations in OpenAlex.
- Investigating the Efficacy of Various Photosensitizers and Irradiation Strategies in Antimicrobial Photodynamic Inactivation on Different Types of Microbes.International journal of molecular sciences · 2026Article
- NMR Based Real-Time Analysis of Exometabolites Decodes the Mechanism of Action of Antibacterial Molecules, Nanoparticles, and Materials.Analytical chemistry · 2026Article
- Metabolomics Analysis Provides Insights into the Antibacterial Activity of Curcumin-Based Photodynamic Treatment AgainstFoods (Basel, Switzerland) · 2026Article
- Oral Administration ofAnimals : an open access journal from MDPI · 2026Article
- Photodynamic therapy for caries management: mechanisms, applications, and perspectives.Frontiers in cellular and infection microbiology · 2026Review
- The Photodynamic Antibacterial Potential of New Tetracationic Zinc(II) Phthalocyanines Bearing 4-((Diethylmethylammonium)methyl)phenoxy Substituents.International journal of molecular sciences · 2025Article
- Photodynamic Inactivation of Bacteria in Boar Semen with Blue LED Light.Microorganisms · 2025Article
- Research in etiology of Floppy Kid Syndrome.Frontiers in veterinary science · 2025Article
- Article
- Fertility after photodynamic inactivation of bacteria in extended boar semen.Frontiers in microbiology · 2024Article
- Interaction of Methylene Blue with Severe Acute Respiratory Syndrome Coronavirus 2 Envelope Revealed by Molecular Modeling.International journal of molecular sciences · 2023Article
- The Effect of Antimicrobial Photodynamic Inactivation on the Protein Profile of DormantInternational journal of molecular sciences · 2023Article
- Development of a Polymeric Film Entrapping Rose Bengal and Iodide Anion for the Light-Induced Generation and Release of Bactericidal Hydrogen Peroxide.International journal of molecular sciences · 2022Article
- TheMicroorganisms · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
The worldwide threat of antibiotic resistance requires alternative strategies to fight bacterial infections. A promising approach to support conventional antibiotic therapy is the antimicrobial photodynamic inactivation (aPDI). The aim of this work was to show further insights into the antimicrobial photodynamic principle using two photosensitizers (PS) of different chemical classes, Methylene Blue (MB) and TMPyP, and the organisms Escherichia coli and Staphylococcus aureus as Gram-negative and Gram-positive representatives. Planktonic cultures of both species were cultured under aerobic conditions for 24 h followed by treatment with MB or TMPyP at various concentrations for an incubation period of 10 min and subsequent irradiation for 10 min. Ability to replicate was evaluated by CFU assay. Accumulation of PS was measured using a spectrophotometer. The cytoplasmic membrane integrity was investigated by flow cytometry using SYBR Green and propidium iodide. In experiments on the replication ability of bacteria after photodynamic treatment with TMPyP or MB, a killing rate of 5 log
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