Evidence map›Paper›PMID 35061151›Full record

ArticleInflammation2022

Diallyl Disulfide Attenuates STAT3 and NF-κB Pathway Through PPAR-γ Activation in Cerulein-Induced Acute Pancreatitis and Associated Lung Injury in Mice.

Mathan Kumar Marimuthu, Anbalagan Moorthy, Tamizhselvi Ramasamy

Abstract read
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In one paragraph

Article in Inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mathan Kumar MarimuthuSchool of Biological Science, Vellore Institute of Technology, Vellore, Tamil Nadu, India.
Anbalagan MoorthySchool of Biological Science, Vellore Institute of Technology, Vellore, Tamil Nadu, India.
Tamizhselvi RamasamySchool of Biological Science, Vellore Institute of Technology, Vellore, Tamil Nadu, India. tamizhselvi.r@vit.ac.in.ORCID http://orcid.org/0000-0002-8945-6308
Vellore Institute of Technology University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have previously shown that diallyl disulfide (DADS) protects mice against cerulein-induced acute pancreatitis (AP) and associated lung injury. However, the molecular mechanisms underlying its effect and the components involved have not been studied. We hypothesized that DADS may reduce TNF-α, CSE expression, H

Indexed as

Allyl CompoundsAnimalsAnti-Inflammatory AgentsCeruletideDisulfidesLungLung InjuryMaleMiceNF-kappa BPancreasPancreatitisPPAR gammaRandom AllocationSignal TransductionSTAT3 Transcription FactorAllyl CompoundsAnti-Inflammatory AgentsCeruletidediallyl disulfideDisulfidesNF-kappa BPPAR gammaStat3 protein, mouseSTAT3 Transcription FactorAcute pancreatitisCystathionine-γ-lyasePPAR-γSOCS3.STAT3

Identifiers

PMID35061151
OpenAlexW4206553335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.