Evidence map›Paper›PMID 35061118›Full record

ArticleJournal of medical ultrasonics (2001)2022

Shear wave speed measurement bias in a viscoelastic phantom across six ultrasound elastography systems: a comparative study with transient elastography and magnetic resonance elastography.

Riwa Kishimoto, Mikio Suga, Masashi Usumura, Hiroko Iijima, Masahiro Yoshida, Hiroyuki Hachiya, Tsuyoshi Shiina, Makoto Yamakawa, Kei Konno, Takayuki Obata and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medical ultrasonics (2001), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Liver Stiffness Characterization of OGTJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Riwa KishimotoApplied MRI Research, Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba, Japan.
Mikio SugaCenter for Frontier Medical Engineering, Chiba University, 1-33 Yayoi, Inage, Chiba, Chiba, 263-8522, Japan. mikio.suga@faculty.chiba-u.jp.ORCID http://orcid.org/0000-0003-1663-7092
Masashi UsumuraGraduate School of Science and Engineering, Chiba University, Chiba, Japan.
Hiroko IijimaUltrasound Imaging Center, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
Masahiro YoshidaUltrasound Imaging Center, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
Hiroyuki HachiyaSchool of Engineering, Tokyo Institute of Technology, Meguro, Tokyo, Japan.
Tsuyoshi ShiinaGraduate School of Medicine, Kyoto University, Kyoto, Japan.
Makoto YamakawaGraduate School of Medicine, Kyoto University, Kyoto, Japan.
Kei KonnoClinical Laboratory Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
Takayuki ObataApplied MRI Research, Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba, Japan.
Tadashi YamaguchiCenter for Frontier Medical Engineering, Chiba University, 1-33 Yayoi, Inage, Chiba, Chiba, 263-8522, Japan.
Chiba University · JPHyogo Medical University · JPKyoto University · JPNational Institutes for Quantum Science and Technology · JPJichi Medical University · JPTokyo Institute of Technology · JP

Funding

Japan Society for the Promotion of Science JP17H02115Japan Society for the Promotion of Science JP17H05279Japan Society for the Promotion of Science JP19K08242
6 · The paper itself

Abstract

purposeTo quantify the bias of shear wave speed (SWS) measurements in a viscoelastic phantom across six different ultrasound (US) systems and to compare the SWS with those from transient elastography (TE) and magnetic resonance elastography (MRE).

methodsA viscoelastic phantom of stiffness representing fibrotic liver or healthy thyroid was measured with nine (linear probe) and 10 (convex probe) modes of six different US-based shear wave elastography (SWE) systems using linear and convex probes. SWS measurements of three regions of interest were repeated thrice at two focal depths, coupling the probe to the phantom using a jig. An MRE system using three motion-encoding gradient frequencies of 60, 90, and 120 Hz and TE were also used to measure the stiffness of the phantom.

resultsThe SWS from different SWE systems had mean coefficients of variation of 9.0-9.2% and 5.4-5.6% with linear and convex probes, respectively, in viscoelastic phantom measurement. The focal depth was a less significant source of SWS variability than the system. The total average SWS obtained with US-SWE systems was 19.9% higher than that obtained with MRE at 60 Hz, which is commonly used in clinical practice, and 31.5% higher than that obtained with TE using the M probe.

conclusionsDespite the measurement biases associated with the SWE systems, biases were not necessarily consistent, and they changed with the probes used and depth measured. The SWS of the viscoelastic phantom obtained using different modalities increased according to the shear wave frequency used.

Indexed as

Elasticity Imaging TechniquesBiasHumansLiverLiver CirrhosisPhantoms, ImagingUltrasonographyMagnetic resonance elastographyPhantomQuantitative imaging biomarker allianceUltrasound elastographyViscoelasticity

Identifiers

PMID35061118
PMCPMC9038798
OpenAlexW4206088294

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.