Evidence map›Paper›PMID 35060907›Full record

ArticleJMIR research protocols2022

Mobile Phone-Based Intervention Among Adolescents Living With Perinatally Acquired HIV Transitioning from Pediatric to Adult Care: Protocol for the Interactive Transition Support for Adolescents Living With HIV using Social Media (InTSHA) Study.

Brian C Zanoni, Moherndran Archary, Thobekile Sibaya, Madeleine Goldstein, Scarlett Bergam, David Denton, Vincente Cordero, Cynthia Peng, Christina Psaros, Vincent C Marconi and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in JMIR research protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03624413 (InTSHA), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03624413 nacompletednot on this map

InTSHA: Interactive Transition Support for HIV-infected Adolescents Using Social Media

TypeinterventionalSponsorEmory UniversityRan2021 to 2022Enrolled80ConditionsHIV-1-infection, Adolescent BehaviorArmsSocial Media Intervention, Standard of Care
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
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  4. "AIDS care · 2026
    Article
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  7. Review
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  9. Health Care Transitions Among Adolescents and Young Adults With Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Review
  10. Article
  11. Article
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  13. The Impact of Technology on Adolescent Sexual and Reproductive Needs.International journal of environmental research and public health · 2022
    Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brian C ZanoniSchool of Medicine, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-8640-7703
Moherndran ArcharyNelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.ORCID https://orcid.org/0000-0003-3082-9234
Thobekile SibayaNelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.ORCID https://orcid.org/0000-0001-6819-9712
Madeleine GoldsteinSchool of Medicine, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-5389-2597
Scarlett BergamNelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.ORCID https://orcid.org/0000-0001-6550-8508
David DentonRollins School of Public Health, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0003-2862-5080
Vincente CorderoRollins School of Public Health, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-1371-6249
Cynthia PengSchool of Medicine, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0003-2667-8381
Christina PsarosMassachusetts General Hospital, Boston, MA, United States.ORCID https://orcid.org/0000-0002-0705-2239
Vincent C MarconiSchool of Medicine, Emory University, Atlanta, GA, United States.ORCID https://orcid.org/0000-0001-8409-4689
Jessica E HabererMassachusetts General Hospital, Boston, MA, United States.ORCID https://orcid.org/0000-0001-5845-3190

Funding

Optimizing mHealth for adherence monitoring and interventionK24MH114732 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI HABERER, JESSICA ELIZABETH · 2017 to 2021
$800k
INTSHA: INTERACTIVE TRANSITION SUPPORT FOR HIV-INFECTED ADOLESCENTS USING SOCIAL MEDIAK23MH114771 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI ZANONI, BRIAN C. · 2018 to 2021
$778k
NIMH NIH HHS K23 MH114771NIMH NIH HHS K24 MH114732
6 · The paper itself

Abstract

backgroundAdolescents living with perinatally acquired HIV often have poor retention in care and viral suppression during the transition from pediatric to adult-based care.

objectiveThe aim of this study is to evaluate a mobile phone-based intervention, Interactive Transition Support for Adolescents Living With HIV using Social Media (InTSHA), among adolescents living with perinatally acquired HIV as they transition from pediatric to adult care in South Africa.

methodsInTSHA uses encrypted, closed group chats delivered via WhatsApp (Meta Platforms Inc) to develop peer support and improve communication between adolescents, their caregivers, and health care providers. The intervention is based on formative work with adolescents, caregivers, and health care providers and builds on several existing adolescent support programs as well as the Social-ecological Model of Adolescent and Young Adult Readiness for Transition (SMART). The final InTSHA intervention involves 10 modules conducted weekly through moderated WhatsApp group chats with adolescents and separately with their caregivers. We will randomly assign 80 South African adolescents living with perinatally acquired HIV who are aware of their HIV status and aged between 15 and 19 years to receive either the intervention (n=40) or standard of care (n=40).

resultsWe will measure acceptability of the intervention as the primary outcome and evaluate feasibility and preliminary effectiveness for retention in care and viral suppression after completion of the intervention and at least 6 months after randomization. In addition, we will measure secondary outcomes evaluating the impact of the InTSHA intervention on peer support, self-esteem, depression, stigma, sexual education, connection to health care providers, and transition readiness. Enrollment began on April 15, 2021. As of December 31, 2021 a total of 78 out of expected 80 participants have been enrolled.

conclusionsIf successful, the intervention will be evaluated in a fully powered randomized controlled trial with a larger number of adolescents from urban and rural populations to further evaluate the generalizability of InTSHA.

trial registrationClinicalTrials.gov NCT03624413; https://clinicaltrials.gov/ct2/show/NCT03624413. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/35455.

Indexed as

adolescentcaregiverhealth care providerHIVInTSHAmHealthprotocolSocial mediaSouth Africasupporttransition supportWhatsApp

Identifiers

PMID35060907
PMCPMC8817214

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.