Evidence map›Paper›PMID 35060900›Full record

ArticleeLife2022

A δ-cell subpopulation with a pro-β-cell identity contributes to efficient age-independent recovery in a zebrafish model of diabetes.

Claudio Andrés Carril Pardo, Laura Massoz, Marie A Dupont, David Bergemann, Jordane Bourdouxhe, Arnaud Lavergne, Estefania Tarifeño-Saldivia, Christian Sm Helker, Didier Yr Stainier, Bernard Peers and 2 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  14. Review
  15. Review
  16. Pancreatic δ Cells: An Overlooked Cell in Focus.Advances in anatomy, embryology, and cell biology · 2024
    Review
  17. Article
  18. β-Cell Regeneration Is Driven by Pancreatic Plasticity.Advances in anatomy, embryology, and cell biology · 2024
    Review
  19. Article
  20. An inducible model of chronic hyperglycemia.Disease models & mechanisms · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 4 countries.

Claudio Andrés Carril Pardo *Zebrafish Development and Disease Models laboratory, GIGA-Stem Cells, University of Liège, Liège, Belgium.
Laura Massoz *Zebrafish Development and Disease Models laboratory, GIGA-Stem Cells, University of Liège, Liège, Belgium.
Marie A Dupont *Zebrafish Development and Disease Models laboratory, GIGA-Stem Cells, University of Liège, Liège, Belgium.
David BergemannZebrafish Development and Disease Models laboratory, GIGA-Stem Cells, University of Liège, Liège, Belgium.
Jordane BourdouxheZebrafish Development and Disease Models laboratory, GIGA-Stem Cells, University of Liège, Liège, Belgium.
Arnaud LavergneZebrafish Development and Disease Models laboratory, GIGA-Stem Cells, University of Liège, Liège, Belgium.
Estefania Tarifeño-SaldiviaZebrafish Development and Disease Models laboratory, GIGA-Stem Cells, University of Liège, Liège, Belgium.
Christian Sm HelkerDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
Didier Yr StainierDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.ORCID 0000-0002-0382-0026
Bernard PeersZebrafish Development and Disease Models laboratory, GIGA-Stem Cells, University of Liège, Liège, Belgium.
Marianne M VozZebrafish Development and Disease Models laboratory, GIGA-Stem Cells, University of Liège, Liège, Belgium.
Isabelle ManfroidZebrafish Development and Disease Models laboratory, GIGA-Stem Cells, University of Liège, Liège, Belgium.ORCID 0000-0003-3445-3764
University of Liège · BEMax Planck Institute for Heart and Lung Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Restoring damaged β-cells in diabetic patients by harnessing the plasticity of other pancreatic cells raises the questions of the efficiency of the process and of the functionality of the new

Indexed as

AnimalsDiabetes Mellitus, ExperimentalFemaleInsulinInsulin-Secreting CellsMalePancreasSomatostatinSomatostatin-Secreting CellsZebrafishInsulinSomatostatincell biologydiabetesinsulinpancreasregenerationsomatostatinzebrafish

Identifiers

PMID35060900
PMCPMC8820734
OpenAlexW4206395466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.