ArticleAnnals of medicine2022
A practical nomogram based on systemic inflammatory markers for predicting portal vein thrombosis in patients with liver cirrhosis.
Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 50 citations in OpenAlex.
- Inflammatory burden index predicts arteriogenic erectile dysfunction: a mediation analysis involving the TyG index.Sexual medicine · 2026Article
- An interpretable machine learning approach using nnU-Net-based radiomics for preoperative risk stratification of thymic epithelial tumors: a multicenter study.BMC medical imaging · 2026Article
- Mendelian randomization identifies causal effects of phospholipids on portal vein thrombosis risk: FADS1/2-mediated pathways and their potential as diagnostic biomarkers.Nutrition & metabolism · 2026Article
- Pathogen distribution, antimicrobial resistance, and gut microbiota dysbiosis in patients with cirrhosis complicated by infection in northwestern China.Frontiers in microbiology · 2026Article
- Beyond Rebalanced Haemostasis: Haemostatic Phenotypes, Thrombin Generation, and Clinical Risk in Chronic Liver Disease.TH open : companion journal to thrombosis and haemostasis · 2026Review
- A Retrospective Analysis of 581 Cases of Esophagogastric Variceal Bleeding Complicated by Portal Vein Thrombosis at a Single Center.Canadian journal of gastroenterology & hepatology · 2026Article
- Associations of inflammation-related hematological profile with the early-stages of cardiovascular-kidney-metabolic syndrome and the mediating role of body composition: evidence from the China National Health Survey.Diabetology & metabolic syndrome · 2025Article
- Article
- Portal Vein Thrombosis in Liver Cirrhosis: A Review of Risk Factors and Predictive Indicators.Journal of clinical and translational hepatology · 2025Review
- [Research progress on predictive models of portal vein thrombosis in liver cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Review
- Association between the inflammatory burden index and erectile dysfunction: a cross-sectional study based on NHANES 2001-2004.Journal of health, population, and nutrition · 2025Article
- A Novel "Personalized Safe Zone" for Acetabular Cup Placement During Total Hip Arthroplasty in Patients With Spinopelvic Pathology: Concept, Construction, and Clinical Application.Orthopaedic surgery · 2025Article
- Nomogram model for identifying portal vein thrombosis in patients with decompensated cirrhosis.European journal of gastroenterology & hepatology · 2025Article
- Construction of a Nomogram for Portal Vein Thrombosis After Endoscopic Therapy of Severe Gastroesophageal Varices in Cirrhotic Patients.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025Article
- Article
- [Effect of portal vein thrombosis on the long-term prognosis of patients with hepatitis B cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Article
- Inflammatory indicators derived from complete blood counts in relation to osteoarthritis prevalence: findings from the NHANES 2007-2020 cross-sectional survey.Experimental biology and medicine (Maywood, N.J.) · 2025Article
- The relationship between complete blood cell count-derived inflammatory biomarkers and erectile dysfunction in the United States.Scientific reports · 2024Article
- The Imbalance of Homeostasis in Neutrophil Extracellular Traps is Associated with Portal Vein Thrombosis in Patients with Decompensated Cirrhosis.Journal of clinical and translational hepatology · 2024Article
- Nomogram based on lymphocyte-associated inflammatory indexes predicts portal vein thrombosis after splenectomy with esophagogastric devascularization.BMC gastroenterology · 2024Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionImmunothrombosis has recently been used to describe the responses/mechanisms in thrombosis. Systemic inflammatory markers are prognostic markers for a variety of thrombotic conditions; however, their potential value in predicting portal vein thrombosis (PVT) is unknown. This study aimed to establish an easy-to-use nomogram based on systemic inflammatory markers to predict portal vein thrombosis (PVT) in patients with liver cirrhosis. PATIENTS AND
methodsThis retrospective study included 478 patients with cirrhosis between January 2013 and January 2021. Reputed systemic inflammatory markers (systemic immune-inflammation index [SII], neutrophil-to-lymphocyte ratio [NLR], monocyte-to-lymphocyte ratio [MLR], and platelet-to-lymphocyte ratio (PLR)) were measured, and the clinical data were recorded. The independent risk factors for PVT were determined using univariate analyses and multivariate logistic regression analyses, and a nomogram to predict the occurrence of PVT was established. The concordance index, receiver operating characteristic curves, and calibration plots were used to evaluate the performance of the model.
resultsA total of 239 patients with PVT and 239 patients without PVT were selected. In the univariate analysis, high SII, NLR, PLR, and MLR were significantly associated with PVT. NLR and PLR were independent risk factors for PVT (
conclusionsPVT in patients with cirrhosis is associated with increased levels of systemic inflammatory markers. We successfully developed a practical nomogram based on NLR and PLR to accurately predict PVT, which is a practical method helping clinicians rapidly and conveniently diagnose and guide the treatment of PVT in patients with cirrhosis.Key MessagesThe present study is the first report on a nomogram based on systemic inflammatory markers in patients with portal vein thrombosis (PVT).The nomogram had good predictive efficiency and a good clinical application value for predicting PVT in patients with cirrhosis.
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