Evidence map›Paper›PMID 35060778›Full record

ArticleThe Journal of urology2022

Reliability and Validity of Pain and Urinary Symptom Severity Assessment in Urological Chronic Pelvic Pain: A MAPP Network Analysis.

Bruce D Naliboff, Kenneth Locke, Andrew D Schrepf, James W Griffith, Robert Moldwin, John N Krieger, Larissa V Rodriguez, J Quentin Clemens, H Henry Lai, Siobhan Sutcliffe and 5 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 1 country.

Bruce D NaliboffDepartment of Medicine, University of California, Los Angeles, California.
Kenneth LockeDepartment of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Andrew D SchrepfDepartment of Anesthesiology, University of Michigan, Ann Arbor, Michigan.
James W GriffithDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Robert MoldwinDepartment of Urology, Hofstra North Shore-LIJ School of Medicine, New Hyde Park, New York.
John N KriegerDepartment of Urology, University of Washington, Seattle, Washington.
Larissa V RodriguezDepartment of Urology, Weill Cornell Medicine, New York, New York.
J Quentin ClemensDepartment of Urology, Division of Neurourology and Pelvic Reconstructive Surgery, University of Michigan, Ann Arbor, Michigan.
H Henry LaiDepartments of Surgery (Urology) and Anesthesiology, Washington University School of Medicine, St Louis, Missouri.
Siobhan SutcliffeDepartment of Surgery and the Alvin J. Siteman Cancer Center, Division of Public Health Sciences, Washington University School of Medicine, St. Louis, Missouri.
Bayley J TapleDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
David WilliamsDepartment of Anesthesiology, University of Michigan, Ann Arbor, Michigan.
Michael A PontariDepartment of Urology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Chris MullinsNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
J Richard LandisDepartment of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
University of Michigan–Ann Arbor · USNorthwestern University · USUniversity of Pennsylvania · USAlvin J. Siteman Cancer CenterHofstra University · USNational Institutes of Health · USTemple University · USUniversity of California, Los Angeles · USUniversity of Washington · USWashington University in St. Louis · USWeill Cornell Medicine · US

Funding

MAPP Research NetworkU01DK082316 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI LANDIS, J RICHARD · 2008 to 2018
$17.2M
Role of CNS in Modulation of Pelvic Pain SyndromeU01DK082342 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KLUMPP, DAVID J · 2008 to 2021
$10.5M
Urology Chronic Pelvic Pain Longitudinal Symptom Patterns StudyU01DK082344 · NIDDK · UNIVERSITY OF IOWA · PI KREDER, KARL J · 2008 to 2021
$9.8M
University of Michigan MAPP Research Network Discovery SiteU01DK082345 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CLAUW, DANIEL J, CLEMENS, J. QUENTIN · 2008 to 2021
$9.7M
Neurobiological endophenotypes & gene-environment interactions in IC/PBS & in aU01DK082370 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KUTCH, JASON J., MAYER, EMERAN A · 2008 to 2021
$9.2M
WSU Urologic Chronic Pelvic Pain Syndromes Discovery CenterU01DK082325 · NIDDK · WASHINGTON STATE UNIVERSITY · PI BOGIC, MARIJA · 2008 to 2021
$9.0M
Washington University MAPP Network Discovery SiteU01DK082315 · NIDDK · WASHINGTON UNIVERSITY · PI LAI, HING HUNG HENRY · 2008 to 2021
$9.0M
MAPP Research Network Tissue Analysis and Technology CoreU01DK082333 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI LUCIA, M. SCOTT · 2008 to 2018
$6.1M
Limited Competition for Continuation of the MAPP-RN DCCU24DK082316 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI LANDIS, J RICHARD · 2019 to 2021
$4.9M
Expansion of the MAPP Research Network: Microbial and Biopsychosocial ContributioU01DK103271 · NIDDK · QUEEN'S UNIVERSITY AT KINGSTON · PI NICKEL, JOHN CURTIS · 2014 to 2018
$1.2M
Discovery, Validation and Clinical Application of Novel, Non-Invasive BiomarkersU01DK103227 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI LEE, RICHARD SANG-YONG, MOSES, MARSHA A · 2014 to 2018
$1.2M
Microbiome and Proteome As Predictive Biomarkers of UCPPSU01DK103260 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI ANGER, JENNIFER TASH, FREEMAN, MICHAEL R · 2014 to 2018
$1.2M
NIDDK NIH HHS U01 DK082315NIDDK NIH HHS U01 DK082316NIDDK NIH HHS U01 DK082325NIDDK NIH HHS U01 DK082333NIDDK NIH HHS U01 DK082342NIDDK NIH HHS U01 DK082344NIDDK NIH HHS U01 DK082345NIDDK NIH HHS U01 DK082370NIDDK NIH HHS U01 DK103227NIDDK NIH HHS U01 DK103260NIDDK NIH HHS U01 DK103271NIDDK NIH HHS U24 DK082316NIDDK NIH HHS U24 DK082333
6 · The paper itself

Abstract

purposeWe assessed the reliability and validity of an efficient severity assessment for pelvic pain and urinary symptoms in urological chronic pelvic pain syndrome, which consists of interstitial cystitis/bladder pain syndrome and chronic prostatitis/chronic pelvic pain syndrome. MATERIALS AND

methodsA total of 578 patients were assessed using brief, empirically derived self-report scales for pelvic pain severity (PPS) and urinary symptom severity (USS) 4 times during a 1-month period and baseline clinic visit that included urological, pain and illness-impact measures. Mild, moderate and severe categories on each dimension were examined for measurement stability and construct validity.

resultsPPS and USS severity categories had adequate reliability and both discriminant validity (differential relationships with specific clinical and self-report measures) and convergent validity (common association with nonurological somatic symptoms). For example, increasing PPS was associated with pelvic tenderness and widespread pelvic pain, whereas USS was associated with urgency during a bladder filling test and increased sensory sensitivity. PPS and USS categories were independently associated with nonurological pain and emotional distress. A descriptive analysis identified higher likelihood characteristics associated with having moderate to severe PPS or USS or both. Lack of sex interactions indicated that the measures are comparable in interstitial cystitis/bladder pain syndrome and chronic prostatitis/chronic pelvic pain syndrome.

conclusionsWomen and men with urological chronic pelvic pain syndrome can be reliably subgrouped using brief self-report measures of mild, moderate or severe pelvic pain and urinary symptoms. Comparisons with a broad range of clinical variables demonstrate the validity and potential clinical utility of these classifications, including use in clinical trials, health services and biological research.

Indexed as

Chronic PainCystitis, InterstitialProstatitisFemaleHumansMalePelvic PainReproducibility of ResultsSyndromecystitis, interstitiallower urinary tract symptomspelvic painprostatitis

Identifiers

PMID35060778
PMCPMC10494963
OpenAlexW4205101879

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.