Evidence map›Paper›PMID 35060760›Full record

ArticleThe Journal of urology2022

Frailty Is Associated with an Increased Risk of Complications and Need for Repeat Procedures after Sling Surgery in Older Adults.

Michelle E Van Kuiken, Shoujun Zhao, Kenneth Covinsky, John Boscardin, Emily Finlayson, Anne M Suskind

Open access · greenAbstract read
In one paragraph

Article in The Journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michelle E Van KuikenDepartment of Urology, University of California, San Francisco, California.ORCID 0000-0002-6735-0000
Shoujun ZhaoDepartment of Urology, University of California, San Francisco, California.
Kenneth CovinskyDivision of Geriatric Medicine, University of California, San Francisco, California.
John BoscardinDepartments of Medicine and Epidemiology and Biostatistics, University of California, San Francisco, California.
Emily FinlaysonDepartment of Surgery, University of California, San Francisco, California.
Anne M SuskindDepartment of Urology, University of California, San Francisco, California.
University of California, San Francisco · US

Funding

Optimizing surgical decision-making for nursing home residents undergoing surgery for bladder and bowel dysfunctionR01AG058616 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SUSKIND, ANNE M. · 2018 to 2021
$1.7M
NIA NIH HHS R01 AG058616
6 · The paper itself

Abstract

purposeSling surgery is the gold standard treatment for stress urinary incontinence in women. While data support the use of sling surgery in younger and middle-aged women, outcomes in older, frail women are largely unknown. MATERIALS AND

methodsData were examined for all Medicare beneficiaries ≥65 years old who underwent sling surgery with or without concomitant prolapse repair from 2014 to 2016. Beneficiaries were stratified using the Claims-Based Frailty Index (CFI) into 4 categories: not frail (CFI <0.15), prefrail (0.15 ≤CFI <0.25), mildly frail (0.25 ≤CFI <0.35) and moderately to severely frail (CFI ≥0.35). Outcomes included rates and relative risk of 30-day complications, 1-year mortality and repeat procedures for persistent incontinence or obstructed voiding at 1 year.

resultsA total of 54,112 women underwent sling surgery during the study period, 5.2% of whom were mildly to moderately to severely frail. Compared to the not frail group, moderately to severely frail beneficiaries demonstrated an increased adjusted relative risk (aRR) of 30-day complications (56.5%; aRR 2.5, 95% CI: 2.2-2.9) and 1-year mortality (10.5%; aRR 6.7, 95% CI: 4.0-11.2). Additionally, there were higher rates of repeat procedures in mildly to severely frail beneficiaries (6.6%; aRR 1.4, 95% CI: 1.2-1.6) compared to beneficiaries who were not frail.

conclusionsAs frailty increased, there was an increased relative risk of 30-day complications, 1-year mortality and need for repeat procedures for persistent incontinence or obstructed voiding at 1 year. While there were fewer sling surgeries in performed frail women, the observed increase in complication rates was significant. Frailty should be strongly considered before pursuing sling surgery in older women.

Indexed as

FrailtySuburethral SlingsUrinary IncontinenceUrinary Incontinence, StressAgedFemaleHumansMaleMedicareMiddle AgedUnited Statesagingfrail elderlyfrailtysuburethral slingsurinary incontinence, stress

Identifiers

PMID35060760
PMCPMC9086120
OpenAlexW4205153914

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.