Evidence map›Paper›PMID 35060348›Full record

ArticleThe clinical respiratory journal2022

Yield of chest computed tomography angiogram in cystic fibrosis patients with suspected pulmonary embolism.

Kathleen Suzanne Mahan, Hamna Ahmad, Andrew George Keenan, Matthew Erren Prekker, Robert Ralph Kempainen

Open access · goldAbstract read
In one paragraph

Article in The clinical respiratory journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kathleen Suzanne MahanDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA.
Hamna AhmadDivision of Pulmonary, Allergy, and Critical Care Medicine, Hennepin Healthcare, Minneapolis, Minnesota, USA.
Andrew George KeenanDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA.
Matthew Erren PrekkerDivision of Pulmonary, Allergy, and Critical Care Medicine, Hennepin Healthcare, Minneapolis, Minnesota, USA.
Robert Ralph KempainenDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Minnesota, Twin Cities, Minneapolis, Minnesota, USA.
Hennepin Healthcare Research Institute · USUniversity of Minnesota · US

Funding

TRAINING-PULMONARY CELL &MOLECULAR BIOLOGY &PHYSIOLOGYT32HL007741 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DUDLEY, R. ADAMS, INGBAR, DAVID H · 1994 to 2023
$13.9M
NHLBI NIH HHS T32 HL007741NIH T32 Training Grant 5 T32 HL 7741-24
6 · The paper itself

Abstract

introductionIndividuals with cystic fibrosis (CF) may be at increased risk of pulmonary embolism (PE). Symptoms of PE overlap substantially with those of CF respiratory exacerbations. CF patients commonly undergo chest computed tomography (CT) angiograms (CTPA) to evaluate for PE, but little is known about the clinical presentation and diagnosis of PE in this population.

objectivesThe objectives of this study are to determine the diagnostic yield of CTPA for PE in adult patients with CF and assess the utility of the Revised Geneva Score (RGS) in this population.

methodsRetrospective review of all CTPA results was performed on CF patients with suspected PE at a large CF center from 1 January 2011 through 31 March 2017. Patient demographics, medical history, and presenting signs and symptoms were abstracted by chart review.

resultsA total of 103 unique CTPA studies were performed in 68 patients. Most were hospitalized at the time of CTPA, predominantly for respiratory manifestations of CF. CTPA identified four patients with PE. The small number of positive studies precluded analysis of predictors of PE. Fewer PE were diagnosed than predicted by the Revised Geneva Score, which was intermediate probability in 77/103 (75%) patients.

conclusionThe prevalence of PE in CF patients undergoing CTPA for suspected PE was 4%, which is lower than predicted by the Revised Geneva Score. This may be due to a large overlap in the signs and symptoms of PE and exacerbations of CF lung disease.

Indexed as

Cystic FibrosisPulmonary EmbolismAdultAngiographyComputed Tomography AngiographyHumansRetrospective StudiesTomography, X-Ray Computedcystic fibrosisdiagnostic imagingdisease exacerbationpulmonary embolism

Identifiers

PMID35060348
PMCPMC9060046
OpenAlexW4205778241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.