ArticleClinical neuroradiology2022
Flow Diverter Treatment of Ruptured Basilar Artery Perforator Aneurysms : A Multicenter Experience.
Article in Clinical neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06189014 (The International PERForator ANeurysm Registry), which is not on this map. Cited by 15 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The International PERForator ANeurysm Registry (PERFAN) - Natural History, Treatment, and Outcome of Intracranial Perforator Aneurysms
Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Embolization of ruptured flow-related aneurysms arising from basilar artery perforators feeding lateral pontine arteriovenous malformations: a case series.International journal of surgery case reports · 2026Article
- 7T magnetic resonance angiographic imaging of basilar artery perforator aneurysms - initial experience of a non-invasive alternative to DSA.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Article
- Treatment of a Ruptured Basilar Artery Perforator Aneurysm in the Subacute Phase Using Overlapping LVIS Blue Stents: A Case Report and Review of the Literature.Journal of neuroendovascular therapy · 2026Article
- Successful conservative management for ruptured basilar artery perforator aneurysm associated with early hematoma expansion in right temporal lobe without aneurysm rerupture: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Perimesencephalic non-aneurysmal subarachnoid hemorrhage: is there a need for repeat digital subtraction angiography?Neuroradiology · 2025Article
- Management of Intracranial Perforator Aneurysms.Stroke (Hoboken, N.J.) · 2025Review
- Ruptured Basilar Artery Perforator Aneurysm: Nightmare of a Treating Neurosurgeon.Asian journal of neurosurgery · 2025Article
- Benign versus sinister aetiologies underlying basal cistern subarachnoid haemorrhage: a case series.Journal of medical case reports · 2025Article
- Current research status and future of endovascular treatment for basilar artery aneurysms.The neuroradiology journal · 2024Review
- An unusual etiology of subarachnoid hemorrhage, basilar artery perforator aneurysms, in Macao: Three case reports and review of literature.World journal of clinical cases · 2024Article
- Basilar artery perforator aneurysms: a comparison with non-perforator saccular aneurysms.Acta neurochirurgica · 2024Article
- Two Cases of Subarachnoid Hemorrhage with Microaneurysmal Changes and Spontaneous Disappearance in the Basilar Artery.NMC case report journal · 2024Article
- Utility of flow diverters in treatment of acutely ruptured uncoilable aneurysms of the posterior circulation of the brain.Japanese journal of radiology · 2023Article
- Spontaneous subarachnoid hemorrhage caused by ruptured aneurysm of basilar trunk perforator: a case report and literature review.Chinese neurosurgical journal · 2022Article
- Ruptured basilar artery perforator aneurysm: A two-case correspondence of this rare phenomenon.Brain circulationArticle
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRuptured basilar artery perforator aneurysms (BAPAs) represent a very rare cause of subarachnoid hemorrhage and an under-reported subtype of cerebral aneurysm. There is no consensus for the optimal treatment strategy (conservative vs. surgical vs. various endovascular approaches). We aim to present a multicenter experience of BAPA treatment using flow-diverter (FD) stents.
methodsAt five tertiary neurovascular centers, all cases of ruptured BAPAs treated by FD were retrospectively collected. Baseline imaging and clinical characteristics, complications, as well as early and long-term angiographic and clinical outcome (mRS) were analyzed.
resultsEighteen patients (mean age, 57 years; SD, ±10.7 years) with acute SAH related to a BAPA were treated using 18 FD stents. Aneurysms were detected on initial imaging study in 28%; delayed diagnosis was triggered by clinical deterioration due to rebleeding in 15%. No rebleeding after FD was seen, 28% developed FD-related ischemic complications. At long term (n = 16), overall mortality was 13% (2/16), and favorable outcome (mRS 0-2) was 81% (13/16). All BAPAs (n = 13) were completely occluded at long-term angiographic follow-up.
conclusionIn our multicenter experience, FD treatment of ruptured BAPAs appears to have comparable safety and efficacy outcomes to FD treatment of other ruptured posterior circulation aneurysms as well as to the conservative management of BAPAs. This treatment strategy for a ruptured BAPA achieved a high rate of angiographic occlusion and favorable clinical outcome; however, as the conservative management also seems to offer similar clinical outcomes an individualized treatment decision is warranted. Future prospective studies comparing both approaches are required.
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