Evidence map›Paper›PMID 35059676›Full record

ArticleCurrent research in microbial sciences2022

Indole-containing arene-ruthenium complexes with broad spectrum activity against antibiotic-resistant bacteria.

Victoria C Nolan, Laia Rafols, James Harrison, Joan J Soldevila-Barreda, Marialuisa Crosatti, Natalie J Garton, Malgorzata Wegrzyn, Danielle L Timms, Colin C Seaton, Helen Sendron and 4 more

Open access · goldAbstract read
In one paragraph

Article in Current research in microbial sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Victoria C NolanCollege of Health and Life Sciences, Aston University, B4 7ET, Birmingham, United Kingdom.
Laia RafolsSchool of Chemistry and Biosciences, University of Bradford, BD7 1DP, Bradford, United Kingdom.
James HarrisonCollege of Health and Life Sciences, Aston University, B4 7ET, Birmingham, United Kingdom.
Joan J Soldevila-BarredaSchool of Chemistry and Biosciences, University of Bradford, BD7 1DP, Bradford, United Kingdom.
Marialuisa CrosattiCL3 facility, Division of Biomedical Services, University of Leicester, LE1 7RH, Leicester, United Kingdom.
Natalie J GartonDepartment of Respiratory Sciences and Leicester TB Research Group, University of Leicester, LE1 7RH, Leicester, United Kingdom.
Malgorzata WegrzynCL3 facility, Division of Biomedical Services, University of Leicester, LE1 7RH, Leicester, United Kingdom.
Danielle L TimmsCollege of Health and Life Sciences, Aston University, B4 7ET, Birmingham, United Kingdom.
Colin C SeatonSchool of Chemistry and Biosciences, University of Bradford, BD7 1DP, Bradford, United Kingdom.
Helen SendronSchool of Chemistry and Biosciences, University of Bradford, BD7 1DP, Bradford, United Kingdom.
Maria AzmanovaSchool of Chemistry and Biosciences, University of Bradford, BD7 1DP, Bradford, United Kingdom.
Nicolas P E BarrySchool of Chemistry and Biosciences, University of Bradford, BD7 1DP, Bradford, United Kingdom.
Anaïs Pitto-BarrySchool of Chemistry and Biosciences, University of Bradford, BD7 1DP, Bradford, United Kingdom.
Jonathan A G CoxCollege of Health and Life Sciences, Aston University, B4 7ET, Birmingham, United Kingdom.
University of Bradford · GBAston University · GBUniversity of Leicester · GBUniversité Paris-Saclay · FR

Funding

Wellcome Trust
6 · The paper itself

Abstract

Antimicrobial resistant (AMR) bacteria are emerging and spreading globally, threatening our ability to treat common infectious diseases. The development of new classes of antibiotics able to kill or inhibit the growth of such AMR bacteria through novel mechanisms of action is therefore urgently needed. Here, a new family of indole-containing arene ruthenium organometallic compounds are screened against several bacterial species and drug resistant strains. The most active complex [(

Identifiers

PMID35059676
PMCPMC8760505
OpenAlexW4200155515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.