Evidence map›Paper›PMID 35059660›Full record

ArticleJAAD international2022

Generalized pustular psoriasis in Brazil: A public claims database study.

Gleison Vieira Duarte, André Vicente Esteves de Carvalho, Ricardo Romiti, Antonio Gaspar, Thaís Gomes de Melo, Cinara Prata Soares, Anna Rita Aguirre

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAAD international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Review
  4. Epidemiology of generalized pustular psoriasis in Germany: Analyzing factors influencing prevalence estimates health insurance data.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gleison Vieira DuarteInstituto Bahiano de Imunoterapia - IBIS, Salvador, Brazil.
André Vicente Esteves de CarvalhoHospital Moinhos de Ventos Porto Alegre, Porto Alegre, Brazil.
Ricardo RomitiDermatology Division, University of São Paulo, São Paulo, Brazil.
Antonio GasparHeads in Health - São Paulo, Brazil.
Thaís Gomes de MeloBoehringer Ingelheim do Brasil - Avenida das Nações Unidas, São Paulo, Brazil.
Cinara Prata SoaresBoehringer Ingelheim do Brasil - Avenida das Nações Unidas, São Paulo, Brazil.
Anna Rita AguirreBoehringer Ingelheim do Brasil - Avenida das Nações Unidas, São Paulo, Brazil.
Boehringer Ingelheim (Brazil) · BRUniversidade de São Paulo · BRUniversidade do Vale do Rio dos Sinos · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGeneralized pustular psoriasis (GPP) is a rare and severe phenotype of psoriasis characterized by sudden outbreak of widespread coalescent sterile pustules associated with a spectrum of systemic symptoms.

objectiveWe aimed to describe the epidemiology and treatment of GPP in Brazil from the public health care system perspective.

methodsThis was a retrospective public claims database study, using outpatient and inpatient databases, with information from January 2018 to August 2020, based on records of health resource utilization by patients with GPP. Outpatient treatment regimens and fatal inpatient outcomes were described.

resultsIn total, 1458 outpatients of all ages were identified, of whom 53% were women. We estimated the GPP prevalence in Brazil to be between 0.7 and 0.9 per 100,000. Acitretin was the most commonly dispensed drug. Of all the outpatients, 769 outpatients could be tracked in the inpatient database, and 151 had hospital admissions during the study period. Of them, 5.3% had a fatal outcome during hospitalization. A primary skin condition or an infection was the most frequent hospitalization cause. LIMITATION: The International Classification of Diseases codes for GPP and psoriasis have not been previously validated in this context.

conclusionGPP is a rare disease in Brazil and affects individuals of all ages and both sexes. Hospitalizations and disease-related deaths highlight the need for its prompt diagnosis, close medical follow-up, and effective treatment.

Indexed as

Brazilian public health systemclaims database studyDATASUSDATASUS, Departamento de Informática do Sistema Único de Saúdeepidemiologygeneralized pustular psoriasisGPP, generalized pustular psoriasisICD, International Classification of Diseasespsoriasis hospitalizationpsoriasis treatmentpustular psoriasisPV, psoriasis vulgarisSIA, Sistema de Informações AmbulatoriaisSIH, Sistema de Informações HospitalaresSUS, Sistema Único de Saúde

Identifiers

PMID35059660
PMCPMC8760386
OpenAlexW4205219821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.