Evidence map›Paper›PMID 35059575›Full record

ArticleBeyoglu eye journal2021

Evaluation of Peripapillary Microcirculation in Patients with Acromegaly.

Mine Karahan, Atilim Armagan Demirtas, Leyla Hazar, Sedat Ava, Zafer Pekkolay, Ugur Keklikci

Open access · diamondAbstract read
In one paragraph

Article in Beyoglu eye journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mine KarahanDepartment of Ophthalmology, Dicle University Faculty of Medicine, Diyarbakir, Turkey.ORCID https://orcid.org/0000-0002-3591-721X
Atilim Armagan DemirtasDepartment of Ophthalmology, Health Sciences University, Izmir Tepecik Training and Research Hospital, Izmir, Turkey.ORCID https://orcid.org/0000-0002-6504-8385
Leyla HazarDepartment of Ophthalmology, Dicle University Faculty of Medicine, Diyarbakir, Turkey.ORCID https://orcid.org/0000-0002-8206-781X
Sedat AvaDepartment of Ophthalmology, Dicle University Faculty of Medicine, Diyarbakir, Turkey.ORCID https://orcid.org/0000-0001-8856-0528
Zafer PekkolayDepartment of Endocrinology and Metabolism, Dicle University Faculty of Medicine, Diyarbakir, Turkey.ORCID https://orcid.org/0000-0002-5323-2257
Ugur KeklikciDepartment of Ophthalmology, Dicle University Faculty of Medicine, Diyarbakir, Turkey.ORCID https://orcid.org/0000-0003-2348-4856
Dicle University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate the radial peripapillary capillary (RPC) and the optic nerve head (ONH) perfusion of patients with acromegaly using optical coherence tomography angiography (OCTA).

methodsTwenty-four eyes of 24 acromegaly patients comprised the study group and 24 eyes of 24 healthy individuals were used as a control group. The ONH and RPC vascular density (VD) was measured for each patient using OCTA. The insulin-like growth factor 1 (IGF-1) levels were also recorded and compared.

resultsThe VD of the inferior nasal ONH and nasal RPC was significantly lower in the acromegaly group than in the control group (p=0.047 and p=0.001, respectively). There was a significant negative correlation between the VD of the superior nasal ONH and the IGF-1 level (r=-0.283, p=0.038).

conclusionThe ONH and RPC VD values measured using OCTA were segmentally different in the acromegaly group compared with those of the control group. This method of non-invasive quantitative analysis of retinal perfusion using OCTA may be useful for future studies involving patients with acromegaly.

Indexed as

Acromegalyoptical coherence tomography angiographyoptic nerve headvascular density

Identifiers

PMID35059575
PMCPMC8759556
OpenAlexW3199271820

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.