Evidence map›Paper›PMID 35059419›Full record

ArticleFrontiers in medicine2021

The Association of an Alpha-2 Adrenergic Receptor Agonist and Mortality in Patients With COVID-19.

John L Hamilton, Mona Vashi, Ekta B Kishen, Louis F Fogg, Markus A Wimmer, Robert A Balk

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

John L HamiltonDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, United States.
Mona VashiDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, United States.
Ekta B KishenBioinformatics and Biostatistics Core, Rush University Medical Center, Chicago, IL, United States.
Louis F FoggDepartment of Community, Systems and Mental Health Nursing, Rush University Medical Center, Chicago, IL, United States.
Markus A WimmerDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, United States.
Robert A BalkDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, United States.
Rush University Medical Center · US

Funding

Pre and Post-Doctoral Training in Joint HealthT32AR073157 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI D Rick Sumner · 2019 to 2026
$2.3M
NIAMS NIH HHS T32 AR073157
6 · The paper itself

Abstract

There is a need for treatments to reduce coronavirus disease 2019 (COVID-19) mortality. Alpha-2 adrenergic receptor (α

Indexed as

alpha-2 adrenergic receptor agonistcoronavirus disease 2019 (COVID-19)dexmedetomidinemortalitysevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Identifiers

PMID35059419
PMCPMC8764306
OpenAlexW4206394614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.