Evidence map›Paper›PMID 35059320›Full record

ArticleFrontiers in oncology2021

LncRNA KRT19P3 Is Involved in Breast Cancer Cell Proliferation, Migration and Invasion.

Yanping Fan, Xiaotong Dong, Meizeng Li, Pengju Liu, Jie Zheng, Hongli Li, Yunxiang Zhang

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yanping FanPathology Department, First Affiliated Hospital of Weifang Medical University (Weifang People's Hospital), Weifang, China.
Xiaotong DongPathology Department, First Affiliated Hospital of Weifang Medical University (Weifang People's Hospital), Weifang, China.
Meizeng LiPathology Department, First Affiliated Hospital of Weifang Medical University (Weifang People's Hospital), Weifang, China.
Pengju LiuSchool of Economics, Qingdao University, Qingdao, China.
Jie ZhengDepartment of Basic Medicine, Weifang Medical University, Weifang, China.
Hongli LiDepartment of Basic Medicine, Weifang Medical University, Weifang, China.
Yunxiang ZhangPathology Department, First Affiliated Hospital of Weifang Medical University (Weifang People's Hospital), Weifang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (LncRNAs) have already been taken as critical regulatory molecules in breast carcinoma (BC). Besides, the progression of BC is closely associated with the immune system. However, the relationship between lncRNAs and the tumor immune system in BC has not been fully studied. LncRNA KRT19P3 has been reported to inhibit the progression of gastric cancer. In the present study, we first discovered that KRT19P3 was downregulated in BC tissues compared with para cancer tissue. Then we showed that KRT19P3 could be used as a marker to differentiate BC from para cancer tissue. Increased expression of KRT19P3 markedly inhibited the proliferation, migration, and invasion rate of BC cells

Indexed as

breast cancerCD8+ T cellimmuneKRT19P3long non-coding RNAPD-L1

Identifiers

PMID35059320
PMCPMC8763666

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.