Evidence map›Paper›PMID 35059313›Full record

SynthesisFrontiers in oncology2021

Charged Particle Irradiation for Pancreatic Cancer: A Systematic Review of

Dandan Wang, Ruifeng Liu, Qiuning Zhang, Hongtao Luo, Junru Chen, Meng Dong, Yuhang Wang, Yuhong Ou, Zhiqiang Liu, Shilong Sun and 4 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Dandan WangInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Ruifeng LiuInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Qiuning ZhangInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Hongtao LuoInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Junru ChenInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Meng DongInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Yuhang WangInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Yuhong OuInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Zhiqiang LiuInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Shilong SunInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Kehu YangEvidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Jinhui TianEvidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Zheng LiInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Xiaohu WangInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Institute of Modern Physics · CNLanzhou University · CNChinese Academy of Sciences · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGiven the higher precision accompanied by optimized sparing of normal tissue, charged particle therapy was thought of as a promising treatment for pancreatic cancer. However, systematic preclinical studies were scarce. We aimed to investigate the radiobiological effects of charged particle irradiation on pancreatic cancer cell lines.

methodsA systematic literature search was performed in EMBASE (OVID), Medline (OVID), and Web of Science databases. Included studies were

resultsThirteen carbon ion irradiation and seven proton irradiation

conclusionsCurrent

Indexed as

clonogenic survivalDDRinvasionmigrationpancreatic cancerparticle radiationsystematic review

Identifiers

PMID35059313
PMCPMC8764177
OpenAlexW4206116577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.