Evidence map›Paper›PMID 35059149›Full record

ArticleChemical science2021

General stereoretentive preparation of chiral secondary mixed alkylmagnesium reagents and their use for enantioselective electrophilic aminations.

Alexander Kremsmair, Henrik R Wilke, Matthias M Simon, Quirin Schmidt, Konstantin Karaghiosoff, Paul Knochel

Abstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander KremsmairDepartment of Chemistry, Ludwig-Maximilians-Universität München Butenandtstraße 5-13 81377 München Germany paul.knochel@cup.uni-muenchen.de.
Henrik R WilkeDepartment of Chemistry, Ludwig-Maximilians-Universität München Butenandtstraße 5-13 81377 München Germany paul.knochel@cup.uni-muenchen.de.
Matthias M SimonDepartment of Chemistry, Ludwig-Maximilians-Universität München Butenandtstraße 5-13 81377 München Germany paul.knochel@cup.uni-muenchen.de.
Quirin SchmidtDepartment of Chemistry, Ludwig-Maximilians-Universität München Butenandtstraße 5-13 81377 München Germany paul.knochel@cup.uni-muenchen.de.
Konstantin KaraghiosoffDepartment of Chemistry, Ludwig-Maximilians-Universität München Butenandtstraße 5-13 81377 München Germany paul.knochel@cup.uni-muenchen.de.ORCID https://orcid.org/0000-0002-8855-730X
Paul KnochelDepartment of Chemistry, Ludwig-Maximilians-Universität München Butenandtstraße 5-13 81377 München Germany paul.knochel@cup.uni-muenchen.de.ORCID https://orcid.org/0000-0001-7913-4332

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A general preparation of enantiomerically and diastereomerically enriched secondary alkylmagnesium reagents was reported as well as their use for performing highly stereoselective transition-metal free electrophilic aminations leading to α-chiral amines in up to 97% ee. Thus, the reaction of

Identifiers

PMID35059149
PMCPMC8694387

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.