Evidence map›Paper›PMID 35058934›Full record

ArticleFrontiers in immunology2021

CD33 Delineates Two Functionally Distinct NK Cell Populations Divergent in Cytokine Production and Antibody-Mediated Cellular Cytotoxicity.

Maryam Hejazi, Congcong Zhang, Sabrina B Bennstein, Vera Balz, Sarah B Reusing, Melissa Quadflieg, Keven Hoerster, Stefan Heinrichs, Helmut Hanenberg, Sebastian Oberbeck and 13 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. CD33Journal for immunotherapy of cancer · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 5 institutions in 1 country.

Maryam HejaziInstitute for Transplantation Diagnostics and Cell Therapeutics, Heinrich-Heine University, Düsseldorf, Germany.
Congcong ZhangMiltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany.
Sabrina B BennsteinInstitute for Transplantation Diagnostics and Cell Therapeutics, Heinrich-Heine University, Düsseldorf, Germany.
Vera BalzInstitute for Transplantation Diagnostics and Cell Therapeutics, Heinrich-Heine University, Düsseldorf, Germany.
Sarah B ReusingInstitute for Transplantation Diagnostics and Cell Therapeutics, Heinrich-Heine University, Düsseldorf, Germany.
Melissa QuadfliegMiltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany.
Keven HoersterInstitute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Stefan HeinrichsInstitute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Helmut HanenbergDepartment of Pediatrics III, University Children's Hospital, University of Duisburg-Essen, Essen, Germany.
Sebastian OberbeckDepartment of Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital of Bonn, Bonn, Germany.
Marcus NitscheMiltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany.
Sophie CramerMiltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany.
Rita PfeiferMiltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany.
Pranav OberoiGeorg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.
Heiko RühlInstitute of Experimental Hematology and Transfusion Medicine, University Hospital of Bonn, Bonn, Germany.
Johannes OldenburgInstitute of Experimental Hematology and Transfusion Medicine, University Hospital of Bonn, Bonn, Germany.
Peter BrossartDepartment of Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital of Bonn, Bonn, Germany.
Peter A HornInstitute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Florian BaborDepartment of Pediatric Oncology, Hematology and Clinical Immunology, Center for Child and Adolescent Health, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Winfried S WelsGeorg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.
Johannes C FischerInstitute for Transplantation Diagnostics and Cell Therapeutics, Heinrich-Heine University, Düsseldorf, Germany.
Nina MökerMiltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany.
Markus UhrbergInstitute for Transplantation Diagnostics and Cell Therapeutics, Heinrich-Heine University, Düsseldorf, Germany.
Heinrich Heine University Düsseldorf · DEMiltenyi Biotec (Germany) · DEUniversity Hospital Bonn · DEUniversity of Duisburg-Essen · DEGeorg Speyer Haus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The generation and expansion of functionally competent NK cells

Indexed as

Antibody-Dependent Cell CytotoxicityCD56 AntigenCells, CulturedCytokinesCytotoxicity, ImmunologicFlow CytometryGene Expression ProfilingHumansK562 CellsKiller Cells, NaturalProto-Oncogene Proteins c-kitReceptors, Chimeric AntigenReceptors, IgGSialic Acid Binding Ig-like Lectin 3Up-RegulationCD56 AntigenCytokinesNCAM1 protein, humanProto-Oncogene Proteins c-kitReceptors, Chimeric AntigenReceptors, IgGSialic Acid Binding Ig-like Lectin 3CD33-CARcytokine production and cytotoxicityNK cellNK cell expansionRNAseq analysis

Identifiers

PMID35058934
PMCPMC8764454
OpenAlexW4205909170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.