ReviewFrontiers in endocrinology2021
Challenges in the Management of Atrial Fibrillation With Subclinical Hyperthyroidism.
Review in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Indications of over- and undertreatment of hypothyroidism in primary care: a scoping review and evidence mapping.Scandinavian journal of primary health care · 2026Article
- Atrial fibrillation and associated cardiovascular disorders in adults with hyperthyroidism: a retrospective cohort study from two teaching hospitals.Thyroid research · 2026Article
- Impact of Thyroid Hormone Imbalance on Electrocardiographic Parameters: Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Prediction model and scoring system for the risk of atrial fibrillation recurrence in patients with atrial fibrillation and obstructive sleep apnoea syndrome: a retrospective case-control study.BMC cardiovascular disorders · 2025Article
- Enhanced Differentiation of Amiodarone-Induced Thyrotoxicosis Types Using Semi-Quantitative 99mTc-MIBI Uptake Analysis: A Pilot Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Authors' reply: clinical implication of thyroid status in patients with atrial fibrillation.Heart and vessels · 2024Article
- [Arrhythmias in thyroid dysfunction].Herzschrittmachertherapie & Elektrophysiologie · 2024Review
- Epidemiology, prognosis, and challenges in the management of hyperthyroidism-related atrial fibrillation.European thyroid journal · 2024Review
- Prognostic implications of thyroid disease in patients with atrial fibrillation.Heart and vessels · 2024Article
- Iodine-Induced Hyperthyroidism and Long-term Risks of Incident Atrial Fibrillation and Flutter.The Journal of clinical endocrinology and metabolism · 2023Article
- Association of subclinical hypothyroidism with metabolic syndrome components in a group of apparently healthy Syrians: a retrospective cross-sectional study.Annals of medicine and surgery (2012) · 2023Article
- Analysis of Subclinical Thyroid Dysfunction and Metabolic Abnormality in 28568 Healthy People.International journal of endocrinology · 2023Article
- Postischemic Neuroprotection of Aminoethoxydiphenyl Borate Associates Shortening of Peri-Infarct Depolarizations.International journal of molecular sciences · 2022Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
Abstract
Subclinical thyroid disorders have a high prevalence among older individuals and women. Subclinical hypothyroidism is diagnosed by elevated serum levels of thyroid-stimulating hormone (TSH) with thyroxine levels within the reference range, and subclinical hyperthyroidism is diagnosed by low TSH in conjunction with thyroxine and triiodothyronine levels within reference ranges. Atrial fibrillation is the most commonly diagnosed cardiac arrhythmia and has been associated with an increased risk of mortality, heart failure, stroke, and depression. Mechanistic data from animal and human physiology studies as well as observational data in humans support an association of subclinical hyperthyroidism with atrial fibrillation. Guidelines recommend the measurement of TSH in the evaluation of new-onset atrial fibrillation. All patients with overt hyperthyroidism should be treated, and treatment of subclinical hyperthyroidism should be considered in patients older than 65 years with TSH < 0.4 mlU/L, or in younger patients with TSH < 0.1 mlU/L. Guidelines also recommend screening for AF in patients with known hyperthyroidism. Wearable devices that measure the heart electrical activity continuously may be a novel strategy to detect atrial fibrillation in patients at risk. In this review, we explore the interplay between thyroid hormones and atrial fibrillation, management controversies in subclinical hyperthyroidism, and potential strategies to improve the management of atrial fibrillation in patients with subclinical hyperthyroidism.
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