Evidence map›Paper›PMID 35058870›Full record

ArticleFrontiers in neurology2021

Therapeutic Benefits of Short-Arm Human Centrifugation in Multiple Sclerosis-A New Approach.

Chrysoula Kourtidou-Papadeli, Christos A Frantzidis, Christos Bakirtzis, Anatoli Petridou, Sotiria Gilou, Aliki Karkala, Ilias Machairas, Nikolaos Kantouris, Christiane M Nday, Emmanouil V Dermitzakis and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Hypergravity, Microgravity, and Animal Research.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Chrysoula Kourtidou-PapadeliBiomedical Engineering and Aerospace Neuroscience (BEAN), Laboratory of Medical Physics and Digital Innovation, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Christos A FrantzidisBiomedical Engineering and Aerospace Neuroscience (BEAN), Laboratory of Medical Physics and Digital Innovation, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Christos BakirtzisDepartment of Neurology, Multiple Sclerosis Center, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Anatoli PetridouLaboratory of Evaluation of Human Biological Performance, School of Physical Education and Sport Science at Thessaloniki, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Sotiria GilouBiomedical Engineering and Aerospace Neuroscience (BEAN), Laboratory of Medical Physics and Digital Innovation, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Aliki KarkalaGreek Aerospace Medical Association and Space Research (GASMA-SR), Thessaloniki, Greece.
Ilias MachairasBiomedical Engineering and Aerospace Neuroscience (BEAN), Laboratory of Medical Physics and Digital Innovation, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Nikolaos KantourisGreek Aerospace Medical Association and Space Research (GASMA-SR), Thessaloniki, Greece.
Christiane M NdayBiomedical Engineering and Aerospace Neuroscience (BEAN), Laboratory of Medical Physics and Digital Innovation, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Emmanouil V DermitzakisAeromedical Center of Thessaloniki (AeMC), Thessaloniki, Greece.
Eleftherios BakasLaboratory of Aerospace and Rehabilitation Applications "Joan Vernikos", AROGI Rehabilitation Centre, Thessaloniki, Greece.
Vassilis MougiosLaboratory of Evaluation of Human Biological Performance, School of Physical Education and Sport Science at Thessaloniki, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Panagiotis D BamidisBiomedical Engineering and Aerospace Neuroscience (BEAN), Laboratory of Medical Physics and Digital Innovation, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Joan VernikosGreek Aerospace Medical Association and Space Research (GASMA-SR), Thessaloniki, Greece.
Aristotle University of Thessaloniki · GRAHEPA University Hospital · GRThird Way · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Short-arm human centrifugation (SAHC) is proposed as a robust countermeasure to treat deconditioning and prevent progressive disability in a case of secondary progressive multiple sclerosis. Based on long-term physiological knowledge derived from space medicine and missions, artificial gravity training seems to be a promising physical rehabilitation approach toward the prevention of musculoskeletal decrement due to confinement and inactivity. So, the present study proposes a novel infrastructure based on SAHC to investigate the hypothesis that artificial gravity ameliorates the degree of disability. The patient was submitted to a 4-week training programme including three weekly sessions of 30 min of intermittent centrifugation at 1.5-2

Indexed as

artificial gravitybrain plasticitycase reportexpanded disability status scalemuscle oxygenationsecondary progressive multiple sclerosis

Identifiers

PMID35058870
PMCPMC8764123
OpenAlexW4206356074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.