Evidence map›Paper›PMID 35058758›Full record

ArticleFrontiers in behavioral neuroscience2021

Acupuncture Relieves Stress-Induced Depressive Behavior by Reducing Oxidative Stress and Neuroapoptosis in Rats.

Wen-Jing Cheng, Peng Li, Wen-Ya Huang, Yang Huang, Wen-Jie Chen, Yi-Ping Chen, Jun-Liang Shen, Jian-Kun Chen, Na-Sha Long, Xian-Jun Meng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Wen-Jing ChengDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen, China.
Peng LiYueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wen-Ya HuangDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen, China.
Yang HuangDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen, China.
Wen-Jie ChenDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen, China.
Yi-Ping ChenThird Clinical College, Shanxi University of Traditional Chinese Medicine, Taiyuan, China.
Jun-Liang ShenDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen, China.
Jian-Kun ChenDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen, China.
Na-Sha LongDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen, China.
Xian-Jun MengDepartment of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen, China.
Xiamen University · CNShanxi University of Traditional Chinese Medicine · CNYueyang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress is closely related to the occurrence of depression. Acupuncture has been proved to be an effective method for treating depression. In order to explore the mechanism of the antidepressant effect of acupuncture, this study performed acupuncture prevention on chronic unpredictable mild stress (CUMS) depression model rats, and observed the effect of acupuncture on hippocampal oxidative stress and Nrf2 signaling pathway. Male SD rats were randomly divided into control group, CUMS group, acupuncture group, and fluoxetine group (

Indexed as

acupuncturedepressionneuronal apoptosisNrf2/HO-1 signaling pathwayoxidative stress

Identifiers

PMID35058758
PMCPMC8763975
OpenAlexW4205776151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.