Global Cerebral Ischemia in Male Long Evans Rats Impairs Dopaminergic/ΔFosB Signalling in the Mesocorticolimbic Pathway Without Altering Delay Discounting Rates.

Alexandre Morin, Marilou Poitras, Hélène Plamondon

Open access · goldAbstract read

In one paragraph

Article in Frontiers in behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.5field-weighted citation impact, top 42% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

Antinociceptive effect of intermittent fasting via the orexin pathway on formalin-induced acute pain in mice.Scientific reports · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alexandre MorinCerebro-Vascular Accidents and Behavioural Recovery Laboratory, Behavioural Neuroscience Group, School of Psychology, University of Ottawa, Ottawa, ON, Canada.

Marilou PoitrasCerebro-Vascular Accidents and Behavioural Recovery Laboratory, Behavioural Neuroscience Group, School of Psychology, University of Ottawa, Ottawa, ON, Canada.

Hélène PlamondonCerebro-Vascular Accidents and Behavioural Recovery Laboratory, Behavioural Neuroscience Group, School of Psychology, University of Ottawa, Ottawa, ON, Canada.

University of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Global cerebral ischemia (GCI) in rats has been shown to promote exploration of anxiogenic zones of the Elevated-Plus Maze (EPM) and Open Field Test (OFT). This study investigated changes in impulsive choice and/or defensive responses as possible contributors of heightened anxiogenic exploration observed after ischemia. Impulsivity was assessed using delay discounting (DD) paradigms, while the Predator Odour Test (PO) served to assess changes in defensive responses towards a naturally aversive stimulus. Male Long Evans rats underwent 9 days of autoshaping training and 24 days of DD training prior to GCI or sham surgery (

Indexed as

behavioural impulsivitydelay discountingglobal cerebral ischemiaimpulsive choicemesocorticolimbic systempredator odour

Identifiers

PMID35058756

DOI10.3389/fnbeh.2021.770374

PMCPMC8763703

OpenAlexW4206343634

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.