ReviewNature reviews. Nephrology2022
The impact of excessive salt intake on human health.
Review in Nature reviews. Nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 1 synthesis or guideline pooled it, 162 citations in OpenAlex.
- Efficacy of long-term low carbohydrate diets for patients with type 2 diabetes: A systematic review and meta-analysis.Journal of diabetes investigation · 2024Pooled it
- Trial
- Can trigeminal sensations impact saltiness perception? A mini-review.Journal of the science of food and agriculture · 2026Review
- K-SALT Equation for Urinary Sodium Estimation in CKD.Kidney international reports · 2026Article
- Role of estimated salt intake and nutritional status in patients undergoing hemodialysis: a longitudinal analysis.BMC nephrology · 2026Observational
- Article
- Saltiness and Bitterness Perception of KCl-Based Mixed Salts (KCl/NaCl/L-Arginine) Evaluated by the R-Index and Partial Projective Mapping Methods.Foods (Basel, Switzerland) · 2026Article
- Article
- Subnational inequalities and spatially varying associations of elevated blood glucose among women in India: a national district-level biomarkers analysis.BMC public health · 2026Article
- Valorization of a Low-Pulp Brazilian Native Fruit Pitomba (Talisia esculenta Radlk) Through the Production of Nutritive Powders with the Whole Fruit.Plant foods for human nutrition (Dordrecht, Netherlands) · 2026Article
- Article
- Safety of Commercial Cod Products and Potential Impact on Consumers.Foods (Basel, Switzerland) · 2026Article
- Exploring Salt Reduction Strategies: Navigating Policy Implementation in the Middle East.Food science & nutrition · 2026Review
- Dietary Sodium Intake and Risk of Incident Heart Failure in the Southern Community Cohort Study.JACC. Advances · 2026Article
- Comparing Sodium Redistribution, Cooking Performance, Texture, and Sensory Properties of Guar Gum and Semperfresh Salt-Coated Noodles.ACS omega · 2026Article
- The expanding role of Nogo-B in hypertension: linking kidney physiology, endothelial function and inflammation.Journal of hypertension · 2026Review
- Preliminary evidence of extrarenal sodium storage in a large mammal: implications for comparative physiology and hypertension research : Running: Sodium storage in cattle.Pflugers Archiv : European journal of physiology · 2026Article
- Beyond Blood Pressure: Salt Sensitivity as a Cardiorenal Phenotype-A Narrative Review.Life (Basel, Switzerland) · 2026Review
- Neuronal Metabolism of Branched-Chain Amino Acids Alleviates Lifespan Reduction Caused by High-Salt Diet in Drosophila.Journal of molecular neuroscience : MN · 2026Article
- The effects of hypoxia inducible factor-1α in myeloid cells and a high-salt diet in a mouse model of orthodontic tooth movement.Korean journal of orthodontics · 2026Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Intake of salt is a biological imperative, inextricably woven into physiological systems, human societies and global culture. However, excessive salt intake is associated with high blood pressure. As this effect likely drives cardiovascular morbidity and mortality, excessive salt intake is estimated to cause ~5 million deaths per annum worldwide. Animal research has identified various mechanisms by which high salt intake drives disease in the kidney, brain, vasculature and immune system. The potential for therapeutic interventions in many of these pathways has yet to be tested. Salt-reduction interventions lower blood pressure, but for most individuals, 'hidden' salt in processed foods disconnects salt intake from discretionary control. This problem is compounded by growing inequalities in food systems, which form another hurdle to sustaining individual dietary control of salt intake. The most effective salt-reduction interventions have been implemented at the population level and comprise multi-component approaches, involving government, education and the food industry.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.