ReviewCommunications biology2022
How the motor system copes with aging: a quantitative meta-analysis of the effect of aging on motor function control.
Review in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07077460 (Innovative Hand Rehabilitation System With Synchronized Contralateral Haptic Feedback), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Innovative Hand Rehabilitation System With Synchronized Contralateral Haptic Feedback
Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- A systematic investigation reveals dissociable effects of ageing on implicit and explicit components of sensorimotor learning.Nature human behaviour · 2026Pooled it
- The dynamic bodily self across lifespan: Agency, ownership, and the plasticity of internal body models.Psychonomic bulletin & review · 2026Review
- Alpha-Band EEG Modulation as a Potential Aged-Related Biomarker for Biofeedback-Driven Motor-Cognitive Adaptability.Sensors (Basel, Switzerland) · 2026Article
- Older Adult Movement Assessment Through Rehabilitation Software for Upper Limb Exoskeleton.Sensors (Basel, Switzerland) · 2026Article
- Movement span: Extending the discourse on aging beyond life span and health span.Journal of sport and health science · 2026Article
- Article
- Interplay Between Autophagy, Cellular Senescence, and Brain Aging: Neuroprotective Implications of Intermittent Fasting.Cellular and molecular neurobiology · 2026Review
- Motor signs in late life depression relate to altered subcortical synaptic density and gray matter volume: anNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Behavioral and psychophysical characterization of proprioceptive impairment in healthy aging: a hyper-illusory experience of movement.npj aging · 2026Article
- Association of gait, balance, and handgrip strength with cognitive performance in hospitalized older adults: a retrospective analysis.Frontiers in aging neuroscience · 2026Article
- The ageing brain: Cortical overactivation - How does it evolve?The Journal of physiology · 2026Review
- Neural and motor mechanisms of handwriting: from healthy aging to neurodegenerative disorders.Frontiers in aging neuroscience · 2026Review
- Distinct roles of brain network flexibility in motor learning across age.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Motor reaction time in older women with different degrees of sarcopenia: What do electroencephalograms show?Einstein (Sao Paulo, Brazil) · 2026Observational
- Dance-based exercise interventions in older adults: a narrative review examining the effects on depression, cognitive-motor function, mood, and quality of life.Frontiers in psychiatry · 2026Review
- Bilateral neuromuscular adaptation to acute unilateral resistance exercise in healthy older adults.GeroScience · 2025Article
- The brain activation on upper extremity motor control tasks in different forces levels.Scientific reports · 2025Article
- Brain Connectivity, Neural Networks, and Resilience in Aging and Neurodegeneration.The American journal of pathology · 2025Review
- Effects of Healthy Aging on Tongue-Jaw Kinematics During Feeding.Journal of oral rehabilitation · 2025Article
- From fingers to brain: virtual reality-based test capturing fine hand movements predicts cognitive function in older adults.Innovation in aging · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Motor cognitive functions and their neurophysiology evolve and degrade along the lifespan in a dramatic fashion. Current models of how the brain adapts to aging remain inspired primarily by studies on memory or language processes. Yet, aging is strongly associated with reduced motor independence and the associated degraded interaction with the environment: accordingly, any neurocognitive model of aging not considering the motor system is, ipso facto, incomplete. Here we present a meta-analysis of forty functional brain-imaging studies to address aging effects on motor control. Our results indicate that motor control is associated with aging-related changes in brain activity, involving not only motoric brain regions but also posterior areas such as the occipito-temporal cortex. Notably, some of these differences depend on the specific nature of the motor task and the level of performance achieved by the participants. These findings support neurocognitive models of aging that make fewer anatomical assumptions while also considering tasks-dependent and performance-dependent manifestations. Besides the theoretical implications, the present data also provide additional information for the motor rehabilitation domain, indicating that motor control is a more complex phenomenon than previously understood, to which separate cognitive operations can contribute and decrease in different ways with aging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.