Evidence map›Paper›PMID 35058528›Full record

ArticleScientific reports2022

Hippophae rhamnoides L. leaf and twig extracts as rich sources of nutrients and bioactive compounds with antioxidant activity.

Małgorzata Kubczak, Ainur B Khassenova, Bartosz Skalski, Sylwia Michlewska, Marzena Wielanek, Maria Skłodowska, Araylim N Aralbayeva, Zhanar S Nabiyeva, Maira K Murzakhmetova, Maria Zamaraeva and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Sea Buckthorn (Foods (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Małgorzata KubczakDepartment of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland. malgorzata.kubczak@biol.uni.lodz.pl.
Ainur B KhassenovaDepartment of Biotechnology, Faculty of Food Production, Almaty Technological University, Almaty, Kazakhstan.
Bartosz SkalskiDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Sylwia MichlewskaLaboratory of Microscopic Imaging and Specialized Biological Techniques, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Marzena WielanekDepartment of Plant Physiology and Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Maria SkłodowskaDepartment of Plant Physiology and Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Araylim N AralbayevaFaculty of Medicine and Health Care, Farabi Kazakh National University, Al-Farabi av. 71, Almaty, 050040, Kazakhstan.
Zhanar S NabiyevaDepartment of Biotechnology, Faculty of Food Production, Almaty Technological University, Almaty, Kazakhstan.
Maira K MurzakhmetovaDepartment of Biotechnology, Faculty of Food Production, Almaty Technological University, Almaty, Kazakhstan.
Maria ZamaraevaLaboratory of Molecular Biophysics, Department of Microbiology and Biotechnology, Faculty of Biology, University of Bialystok, Bialystok, Poland.
Maria BryszewskaDepartment of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.
Maksim IonovDepartment of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland. maksmi.ionov@biol.uni.lodz.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants have served for centuries as sources of compounds useful for human health such as antioxidant, anti-diabetic and antitumor agents. They are also rich in nutrients that improve the human diet. Growing demands for these compounds make it important to seek new sources for them. Hippophae rhamnoides L. is known as a plant with health-promoting properties. In this study we investigated the chemical composition and biological properties of bioactive components of ethanol extracts from leaves and twigs of H. rhamnoides L. Chemical components such as the total content of phenolic compounds, vitamins and amino acids and the antioxidant activities of these compounds in cellular and cell-free systems were assessed. The results suggest that the studied extracts are rich in bioactive compounds with potent antioxidant properties. Cytotoxicity and hemotoxicity assays showed that the extracts had low toxicity on human cells over the range of concentrations tested. Interaction with human serum albumin was investigated and conformational changes were observed. Our results indicate that leaf and twig extracts of H. rhamnoides L. should be considered as a non-toxic source of bioactive compounds which may be of interest to the food, pharmaceutical and cosmetic industries.

Indexed as

AntioxidantsChromatography, High Pressure LiquidEthanolFlavonoidsFruitHippophaeMicrobial Sensitivity TestsNutrientsPhenolsPlant ExtractsPlant LeavesPolandAntioxidantsEthanolFlavonoidsNutrientsPhenolsPlant Extracts

Identifiers

PMID35058528
PMCPMC8776824

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.