Evidence map›Paper›PMID 35058500›Full record

ArticleScientific reports2022

Application of ensemble machine learning algorithms on lifestyle factors and wearables for cardiovascular risk prediction.

Weiting Huang, Tan Wei Ying, Woon Loong Calvin Chin, Lohendran Baskaran, Ong Eng Hock Marcus, Khung Keong Yeo, Ng See Kiong

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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  7. OptiStack classifier: optimized stacking framework with ensemble feature engineering for enhanced cardiovascular risk prediction.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Weiting Huang *National Heart Centre Singapore, 5 Hospital Drive, Singapore, 169609, Singapore. huang.weiting@singhealth.com.sg.
Tan Wei Ying *Institute of Data Science, National University of Singapore, Singapore, Singapore.
Woon Loong Calvin ChinNational Heart Centre Singapore, 5 Hospital Drive, Singapore, 169609, Singapore.
Lohendran BaskaranNational Heart Centre Singapore, 5 Hospital Drive, Singapore, 169609, Singapore.
Ong Eng Hock MarcusSingapore General Hospital, Singapore, Singapore.
Khung Keong YeoNational Heart Centre Singapore, 5 Hospital Drive, Singapore, 169609, Singapore.
Ng See KiongInstitute of Data Science, National University of Singapore, Singapore, Singapore.
National Heart Centre Singapore · SGNational University of Singapore · SGSingapore General Hospital · SG

Funding

National Research Foundation Singapore AISG-GC-2019-001
6 · The paper itself

Abstract

This study looked at novel data sources for cardiovascular risk prediction including detailed lifestyle questionnaire and continuous blood pressure monitoring, using ensemble machine learning algorithms (MLAs). The reference conventional risk score compared against was the Framingham Risk Score (FRS). The outcome variables were low or high risk based on calcium score 0 or calcium score 100 and above. Ensemble MLAs were built based on naive bayes, random forest and support vector classifier for low risk and generalized linear regression, support vector regressor and stochastic gradient descent regressor for high risk categories. MLAs were trained on 600 Southeast Asians aged 21 to 69 years free of cardiovascular disease. All MLAs outperformed the FRS for low and high-risk categories. MLA based on lifestyle questionnaire only achieved AUC of 0.715 (95% CI 0.681, 0.750) and 0.710 (95% CI 0.653, 0.766) for low and high risk respectively. Combining all groups of risk factors (lifestyle survey questionnaires, clinical blood tests, 24-h ambulatory blood pressure and heart rate monitoring) along with feature selection, prediction of low and high CVD risk groups were further enhanced to 0.791 (95% CI 0.759, 0.822) and 0.790 (95% CI 0.745, 0.836). Besides conventional predictors, self-reported physical activity, average daily heart rate, awake blood pressure variability and percentage time in diastolic hypertension were important contributors to CVD risk classification.

Indexed as

Blood Pressure Monitoring, AmbulatoryHeart Disease Risk FactorsLife StyleMachine LearningAdultAgedAlgorithmsCalciumCoronary Artery DiseaseExerciseFemaleHeart RateHumansHypertensionMaleMiddle AgedCalcium

Identifiers

PMID35058500
PMCPMC8776753
OpenAlexW4206407393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.