Evidence map›Paper›PMID 35058454›Full record

ArticleScientific data2022

An EPA database on the effects of engineered nanomaterials-NaKnowBase.

William K Boyes, Bradley Beach, Gayle Chan, B Lila M Thornton, Paul Harten, Holly M Mortensen

Abstract read
In one paragraph

Article in Scientific data, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William K BoyesCenter for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, 109 T.W. Alexander Drive, Research Triangle Park, Durham, NC, 27709, USA.
Bradley BeachOak Ridge Institute for Science and Education (ORISE) appointee at Office of Research and Development, US Environmental Protection Agency Research Triangle Park, Durham, NC, 27709, USA.ORCID 0000-0003-0804-1352
Gayle ChanOak Ridge Institute for Science and Education (ORISE) appointee at Office of Research and Development, US Environmental Protection Agency Research Triangle Park, Durham, NC, 27709, USA.
B Lila M ThorntonDepartment of Civil & Environmental Engineering, Duke University, Durham, NC, 27708, USA.
Paul HartenCenter for Computational Toxicology and Exposure, Office of Research and Development, U.S. Environmental Protection Agency, 26 West Martin Luther King Drive, MS 483, Cincinnati, Ohio, 45268, USA.
Holly M MortensenCenter for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, 109 T.W. Alexander Drive, Research Triangle Park, Durham, NC, 27709, USA. mortensen.holly@epa.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The US EPA Office of Research and Development (ORD) has conducted a research program assessing potential risks of emerging materials and technologies, including engineered nanomaterials (ENM). As a component of that program, a nanomaterial knowledge base, termed "NaKnowBase", was developed containing the results of published ORD research relevant to the potential environmental and biological actions of ENM. The experimental data address issues such as ENM release into the environment; fate, transport and transformations in environmental media; exposure to ecological species or humans; and the potential for effects on those species. The database captures information on the physicochemical properties of ENM tested, assays performed and their parameters, and the results obtained. NaKnowBase (NKB) is a relational SQL database, and may be queried either with SQL code or through a user-friendly web interface. Filtered results may be output in spreadsheet format for subsequent user-defined analyses. Potential uses of the data might include input to quantitative structure-activity relationships (QSAR), meta-analyses, or other investigative approaches.

Identifiers

PMID35058454
PMCPMC8776817

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.