Evidence map›Paper›PMID 35058299›Full record

ArticleAJNR. American journal of neuroradiology2022

Large Culprit Plaque and More Intracranial Plaques Are Associated with Recurrent Stroke: A Case-Control Study Using Vessel Wall Imaging.

G Wu, H Wang, C Zhao, C Cao, C Chai, L Huang, Y Guo, Z Gong, D L Tirschwell, C Zhu and 1 more

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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  16. The incomplete circle of Willis is associated with vulnerable intracranial plaque features and acute ischemic stroke.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 3 countries.

G WuFrom The School of Medicine (G.W., H.W.), Nankai University, Tianjin, China.ORCID 0000-0003-0016-9132
H WangFrom The School of Medicine (G.W., H.W.), Nankai University, Tianjin, China.ORCID 0000-0002-2457-2375
C ZhaoDepartment of Radiology (C. Zhao), First Central Clinical College, Tianjin Medical University, Tianjin, China.ORCID 0000-0002-1646-645X
C CaoDepartment of Radiology (C. Cao), Tianjin Huanhu Hospital, Tianjin, China.ORCID 0000-0002-1704-3459
C ChaiDepartment of Radiology (C. Chai, L.H., Y.G., S.X.).ORCID 0000-0001-6267-9109
L HuangDepartment of Radiology (C. Chai, L.H., Y.G., S.X.).ORCID 0000-0002-4214-004X
Y GuoDepartment of Radiology (C. Chai, L.H., Y.G., S.X.).ORCID 0000-0002-5678-9552
Z GongNeurology (Z.G.), Tianjin First Central Hospital, School of Medicine, Nankai University, Tianjin, China.ORCID 0000-0001-9053-5655
D L TirschwellDepartment of Neurology (D.L.T.).ORCID 0000-0002-8059-2901
C ZhuRadiology (C. Zhu), University of Washington, Seattle, Washington.ORCID 0000-0001-6898-549X
S XiaDepartment of Radiology (C. Chai, L.H., Y.G., S.X.) xiashuang77@163.com.ORCID 0000-0003-1626-6383
Yan Chai Hospital · HKNankai University · CNChina XD Group (China) · CNNeurology, Inc · USTianjin First Center Hospital · CNTianjin Huanhu Hospital · CNTianjin Medical University · CNUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIntracranial atherosclerotic plaque features are potential factors associated with recurrent stroke, but previous studies only focused on a single lesion, and few studies investigated them with perfusion impairment. This study aimed to investigate the association among whole-brain plaque features, perfusion deficit, and stroke recurrence. MATERIALS AND

methodsPatients with ischemic stroke due to intracranial atherosclerosis were retrospectively collected and categorized into first-time and recurrent-stroke groups. Patients underwent high-resolution vessel wall imaging and DSC-PWI. Intracranial plaque number, culprit plaque features (such as plaque volume/burden, degree of stenosis, enhancement ratio), and perfusion deficit variables were recorded. Logistic regression analyses were performed to determine the independent factors associated with recurrent stroke.

resultsOne hundred seventy-five patients (mean age, 59 [SD, 12] years; 115 men) were included. Compared with the first-time stroke group (

conclusionsLarge culprit plaque and more intracranial plaques were independently associated with recurrent stroke. Performing whole-brain vessel wall imaging may help identify patients with a higher risk of recurrent stroke.

Indexed as

Intracranial ArteriosclerosisPlaque, AtheroscleroticStrokeCase-Control StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective Studies

Identifiers

PMID35058299
PMCPMC8985671
OpenAlexW4205141399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.