Evidence map›Paper›PMID 35058110›Full record

ArticleZeitschrift fur medizinische Physik2022

An external perpendicular magnetic field does not influence survival and DNA damage after proton and carbon ion irradiation in human cancer cells.

Sylvia Kerschbaum-Gruber, Fatima Padilla-Cabal, Elisabeth Mara, Birgit Lohberger, Dietmar Georg, Hermann Fuchs

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zeitschrift fur medizinische Physik, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sylvia Kerschbaum-GruberDepartment of Radiation Oncology, Medical University of Vienna, Vienna, Austria; MedAustron Ion Therapy Center, Wiener Neustadt, Austria.
Fatima Padilla-CabalDepartment of Radiation Oncology, Medical University of Vienna, Vienna, Austria; MedAustron Ion Therapy Center, Wiener Neustadt, Austria.
Elisabeth MaraUniversity of Applied Science, Wiener Neustadt, Austria.
Birgit LohbergerDepartment of Orthopedics and Trauma, Medical University Graz, Graz, Austria.
Dietmar GeorgDepartment of Radiation Oncology, Medical University of Vienna, Vienna, Austria; MedAustron Ion Therapy Center, Wiener Neustadt, Austria.
Hermann FuchsDepartment of Radiation Oncology, Medical University of Vienna, Vienna, Austria; MedAustron Ion Therapy Center, Wiener Neustadt, Austria. Electronic address: hermann.fuchs@meduniwien.ac.at.
MedAustron · ATFachhochschule Wiener Neustadt · ATMedical University of Graz · AT

Funding

Austrian Science Fund FWF P 32103
6 · The paper itself

Abstract

background and purposeMagnetic field effects on the radiobiological effectiveness during treatment of magnetic resonance (MRI) guided particle therapy are being debated. This study aims at assessing the influence of a perpendicular magnetic field on the biological effects in two human cancer cell lines irradiated with proton or carbon ions. METHODS AND MATERIALS: In vitro cell irradiations were performed in water inside a perpendicular magnetic field of 0 and 1T for both protons and carbon ions. Samples were located in the center of a spread-out Bragg peak at 8cm water equivalent depth with a dose averaged linear energy transfer (LET

resultsWithout a magnetic field, RBE

conclusionsApplying a perpendicular magnetic field did not influence the cell survival, DNA repair, nor the biological effectiveness of protons or carbon ions in two human cancer cell lines.

Indexed as

NeoplasmsProton TherapyCarbonCell SurvivalDNA DamageHumansIonsMagnetic FieldsMonte Carlo MethodProtonsWaterCarbonIonsProtonsWaterBiological effectsIn-vitroMagnetic fieldsMRgPTMR guided particle therapyMR guided proton therapy

Identifiers

PMID35058110
PMCPMC9948843
OpenAlexW4206572809

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.