Evidence map›Paper›PMID 35057814›Full record

ReviewBMC biology2022

Articulating the "stem cell niche" paradigm through the lens of non-model aquatic invertebrates.

P Martinez, L Ballarin, A V Ereskovsky, E Gazave, B Hobmayer, L Manni, E Rottinger, S G Sprecher, S Tiozzo, A Varela-Coelho and 1 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
  2. Article
  3. Advancing marine invertebrate cell line research: four key knowledge gaps.In vitro cellular & developmental biology. Animal · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. The salamander blastema within the broader context of metazoan regeneration.Frontiers in cell and developmental biology · 2023
    Review
  8. Gene delivery available in molluscan cells by strong promoter discovered from bivalve-infectious virus.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Open biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 8 countries.

P MartinezDepartament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain. Pedro.martinez@ub.edu.ORCID 0000-0003-3956-7541
L BallarinDepartment of Biology, University of Padova, Via U. Bassi 58/B, 35100, Padova, Italy.
A V EreskovskyAix Marseille University, Avignon Université, CNRS, IRD, IMBE, Marseille, France.
E GazaveUniversité de Paris, CNRS, Institut Jacques Monod, F-75006, Paris, France.
B HobmayerDepartment of Zoology and Center of Molecular Biosciences, University of Innsbruck, Technikerstr. 25, 6020, Innsbruck, Austria.
L ManniDepartment of Biology, University of Padova, Via U. Bassi 58/B, 35100, Padova, Italy.
E RottingerUniversité Côte d'Azur, CNRS, INSERM, Institute for Research on Cancer and Aging, Nice (IRCAN), Nice, France.
S G SprecherDepartment of Biology, University of Fribourg, Chemin du Musee 10, 1700, Fribourg, Switzerland.
S TiozzoSorbonne Université, CNRS, Laboratoire de Biologie du Développement de Villefranche-sur-mer (LBDV), Paris, France.
A Varela-CoelhoITQB NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Av. da República, 2780-157, Oeiras, Portugal.
B RinkevichIsrael Oceanography and Limnological Research, National Institute of Oceanography, Tel Shikmona, P.O. Box 8030, 31080, Haifa, Israel. buki@ocean.org.il.
Centre National de la Recherche Scientifique · FRUniversity of Padua · ITInstitució Catalana de Recerca i Estudis Avançats · ESInstituto de Biologia Experimental e Tecnológica · PTIsrael Oceanographic and Limnological Research · ILUniversität Innsbruck · ATUniversity of Fribourg · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cells (SCs) in vertebrates typically reside in "stem cell niches" (SCNs), morphologically restricted tissue microenvironments that are important for SC survival and proliferation. SCNs are broadly defined by properties including physical location, but in contrast to vertebrates and other "model" organisms, aquatic invertebrate SCs do not have clearly documented niche outlines or properties. Life strategies such as regeneration or asexual reproduction may have conditioned the niche architectural variability in aquatic or marine animal groups. By both establishing the invertebrates SCNs as independent types, yet allowing inclusiveness among them, the comparative analysis will allow the future functional characterization of SCNs.

Indexed as

InvertebratesStem Cell NicheAnimalsStem CellsAdult stem cell (ASCs)Germline stem cells (GSCs)Marine/aquatic organismsPhyletic diversitySelf-renewalStem cell niche (SCN)

Identifiers

PMID35057814
PMCPMC8781081
OpenAlexW4205174400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.