ArticleBMC infectious diseases2022
Analysis of risk factors for early-onset ventilator-associated pneumonia in a neurosurgical intensive care unit.
Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Incidence rate and risk factors of ventilator-associated pneumonia in neurocritical patients with acute cerebrovascular diseases: A systematic review and meta-analysis of observational studies.The Journal of international medical research · 2026Pooled it
- Risk factors and outcomes of ventilator-associated pneumonia: an updated systematic review and meta-analysis.BMC pulmonary medicine · 2025Pooled it
- Efficacy of Intermittent and Continuous Subglottic Secretion Drainage in Preventing the Risk of Ventilator-Associated Pneumonia: A Meta-Analysis of Randomized Control Trials.Medicina (Kaunas, Lithuania) · 2023Pooled it
- The effect of an infection control guideline on the incidence of ventilator-associated pneumonia in patients admitted to the intensive care units.BMC infectious diseases · 2023Trial
- Mortality and Predictors of In-Hospital Death Among Mechanically Ventilated Adults With Gram-Negative Pneumonia.Cureus · 2026Article
- Prevalence and antimicrobial resistance ofFrontiers in microbiology · 2026Article
- Comparison of different colistin sulfate regimens for carbapenem-resistant gram-negative bacteria pneumonia in neurocritical care patients: a retrospective cohort study.Antimicrobial agents and chemotherapy · 2025Article
- Incidence and risk factors of ventilator-associated pneumonia in the intensive care unit: a systematic review and meta-analysis.Journal of thoracic disease · 2024Article
- Prevalence and risk factors for ventilator-associated pneumonia after cardiac surgery: a systematic review and meta-analysis.Journal of thoracic disease · 2024Article
- Assessing Critical Care Nurse's Knowledge and Adherence to Evidence-Base Guidelines for Ventilator-Associated Pneumonia Prevention in Palestinian Hospitals.Nursing research and practice · 2024Article
- Lower respiratory tract infections due to multi‑drug resistant pathogens in central nervous system injuries (Review).Biomedical reports · 2023Review
- Evaluation of a clinical pharmacist-led antimicrobial stewardship program in a neurosurgical intensive care unit: a pre-and post-intervention cohort study.Frontiers in pharmacology · 2023Article
- Performance Assessment of Medical Professionals in Prevention of Ventilator Associated Pneumonia in Intensive Care Units.International journal of general medicine · 2022Article
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5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundVentilator-associated pneumonia (VAP) is a severe infection among patients in the neurosurgery intensive care unit (NICU).
methodsWe retrospectively evaluated risk factors for early-onset ventilator-associated pneumonia (EOVAP) from January 2019 to December 2019 at a NICU. A total of 89 NICU patients who were intubated within 48 h of onset and whose mechanical ventilation time was at least 7 days were enrolled. We evaluated EOVAP that occurred within the first 7 days after the onset of mechanical ventilation. The enrolled patients had no history of chronic lung disease and no clinical manifestations of infection before intubation. Clinical data of patients were recorded, and the incidence of and risk factors for EOVAP were analyzed. Patients were also grouped by age (≥ 65 vs. < 65 years) and whether they had received hypothermia treatment or not.
resultsAmong 89 mechanically ventilated patients (49 men and 40 women; the mean age ± SD was 60.1 ± 14.3 years), 40 patients (44.9%) developed EOVAP within 7 days and 14 patients (15.7%) had a multidrug resistant bacterial infection. Binary logistic regression analysis indicated that older age (≥ 65 years) (odds ratio [OR]:3.53, 95% confidence interval [CI]:1.27-9.79, P = 0.015) and therapeutic hypothermia (OR:3.68, CI:1.10-12.31, p = 0.034) were independent predictors of EOVAP. Levels of peripheral blood leukocytes, neutrophils and platelets were lower in the therapeutic hypothermia group than those who did not receive hypothermia treatment.
conclusionsThis study found that older age (≥ 65 years) and therapeutic hypothermia were independently associated with the risk of EOVAP in NICU patients.
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