Evidence map›Paper›PMID 35057575›Full record

ArticleNutrients2022

Genome-Wide Analysis of Disordered Eating Behavior in the Mexican Population.

José Jaime Martínez-Magaña, Sandra Hernandez, Ana Rosa Garcia, Valeria Cardoso-Barajas, Emmanuel Sarmiento, Beatriz Camarena, Alejandro Caballero, Laura Gonzalez, Jorge Ameth Villatoro-Velazquez, Maria Elena Medina-Mora and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Functional Genomics Studies of Psychiatric Disorders in Individuals of Latin American Populations: A Scoping Review.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2026
    Article
  2. Review
  3. The impact of SETBP1 mutations in neurological diseases and cancer.Genes to cells : devoted to molecular & cellular mechanisms · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

José Jaime Martínez-MagañaLaboratorio de Genómica de Enfermedades Psiquiátricas y Neurodegenerativas, Instituto Nacional de Medicina Genómica, Mexico City 14610, Mexico.ORCID 0000-0003-0390-8252
Sandra HernandezLaboratorio de Farmacogenética, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.
Ana Rosa GarciaUnidad de Investigación, Hospital Psiquiátrico Infantil Juan N. Navarro, Mexico City 14080, Mexico.
Valeria Cardoso-BarajasUnidad de Investigación, Hospital Psiquiátrico Infantil Juan N. Navarro, Mexico City 14080, Mexico.
Emmanuel SarmientoUnidad de Investigación, Hospital Psiquiátrico Infantil Juan N. Navarro, Mexico City 14080, Mexico.
Beatriz CamarenaLaboratorio de Farmacogenética, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.
Alejandro CaballeroUnidad de Trastornos Alimenticios, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.
Laura GonzalezUnidad de Trastornos Alimenticios, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.
Jorge Ameth Villatoro-VelazquezUnidad de Análisis de Datos y Encuestas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.ORCID 0000-0003-2537-858X
Maria Elena Medina-MoraUnidad de Análisis de Datos y Encuestas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.
Marycarmen Bustos-GamiñoUnidad de Análisis de Datos y Encuestas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.
Clara Fleiz-BautistaUnidad de Análisis de Datos y Encuestas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.
Carlos Alfonso Tovilla-ZarateDivisión Académica Multidisciplinaria de Comalcalco, Universidad Juárez Autónoma de Tabasco, Comalcalco 86654, Mexico.ORCID 0000-0001-8170-8171
Isela Esther Juárez-RojopDivisión de Ciencias de la Salud, Universidad Juárez Autónoma de Tabasco, Villahermosa 86100, Mexico.
Humberto NicoliniLaboratorio de Genómica de Enfermedades Psiquiátricas y Neurodegenerativas, Instituto Nacional de Medicina Genómica, Mexico City 14610, Mexico.ORCID 0000-0003-2494-0067
Alma Delia Genis-MendozaLaboratorio de Genómica de Enfermedades Psiquiátricas y Neurodegenerativas, Instituto Nacional de Medicina Genómica, Mexico City 14610, Mexico.
Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz · MXHospital Psiquiatrico Infantil Juan N Navarro · MXNational Institute of Genomic Medicine · MXUniversidad Juárez Autónoma de Tabasco · MX

Funding

Fundación Gonzalo-Rio Arronte S591Instituto Nacional de Medicina Genómica 06/2018/I
6 · The paper itself

Abstract

Alterations in eating behavior characterized eating disorders (ED). The genetic factors shared between ED diagnoses have been underexplored. The present study performed a genome-wide association study in individuals with disordered eating behaviors in the Mexican population, blood methylation quantitative trait loci (blood-meQTL), summary data-based Mendelian randomization (SMR) analysis, and in silico function prediction by different algorithms. The analysis included a total of 1803 individuals. We performed a genome-wide association study and blood-meQTL analysis by logistic and linear regression. In addition, we analyzed in silico functional variant prediction, phenome-wide, and multi-tissue expression quantitative trait loci. The genome-wide association study identified 44 single-nucleotide polymorphisms (SNP) associated at a nominal value and seven blood-meQTL at a genome-wide threshold. The SNPs show enrichment in genome-wide associations of the metabolic and immunologic domains. In the in silico analysis, the SNP rs10419198 (

Indexed as

Genome-Wide Association StudyAdolescentAdultComputer SimulationDNADNA MethylationFeeding and Eating DisordersFeeding BehaviorFemaleGenetic Predisposition to DiseaseHumansMaleMendelian Randomization AnalysisMexicoPolymorphism, Single NucleotideQuantitative Trait LociDNAfeeding and eating disordergenome-wide association studymethylation quantitative trait loci

Identifiers

PMID35057575
PMCPMC8778304
OpenAlexW4206122738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.