Evidence map›Paper›PMID 35057536›Full record

ArticleNutrients2022

The Role of the Western Diet and Oral Microbiota in Parkinson's Disease.

Barbara Zapała, Tomasz Stefura, Tomasz Milewicz, Julia Wątor, Monika Piwowar, Magdalena Wójcik-Pędziwiatr, Magdalena Doręgowska, Alicja Dudek, Zuzanna Jania, Monika Rudzińska-Bar

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Association between oral dysbiosis and Parkinson's disease: a systematic review.Frontiers in cellular and infection microbiology · 2025
    Pooled it
  2. Oral Microbiota Associated With Parkinson'S Disease: A Systematic Review.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
    Pooled it
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  6. Oral microbiota and central nervous system diseases: A review.Neuroprotection (Chichester, England) · 2025
    Review
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  15. Revisiting Alpha-Synuclein Pathways to Inflammation.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Barbara ZapałaDepartment of Clinical Biochemistry, Jagiellonian University Medical College, 31-066 Krakow, Poland.
Tomasz Stefura2nd Department of General Surgery, Jagiellonian University Medical College, 31-008 Krakow, Poland.ORCID 0000-0003-4208-7872
Tomasz MilewiczDepartment of Gynaecological Endocrinology and Gynaecology, Jagiellonian University Medical College, 31-501 Krakow, Poland.
Julia WątorFaculty of Medical Sciences in Zabrze, Medical University of Silesia, 41-800 Katowice, Poland.
Monika PiwowarDepartment of Bioinformatics and Telemedicine, Faculty of Medicine, Jagiellonian University Medical College, 31-034 Krakow, Poland.
Magdalena Wójcik-PędziwiatrDepartment of Neurology, Andrzej Frycz Modrzewski Krakow University, 30-705 Krakow, Poland.
Magdalena DoręgowskaDepartment of Neurology, Andrzej Frycz Modrzewski Krakow University, 30-705 Krakow, Poland.
Alicja Dudek2nd Department of General Surgery, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Zuzanna JaniaDepartment of Clinical Biochemistry, Jagiellonian University Medical College, 31-066 Krakow, Poland.
Monika Rudzińska-BarDepartment of Neurology, Andrzej Frycz Modrzewski Krakow University, 30-705 Krakow, Poland.ORCID 0000-0002-1453-6856
Jagiellonian University · PLAndrzej Frycz Modrzewski Krakow University · PLMedical University of Silesia · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The type of diet not only affects the composition of the oral microflora but is also one of the more critical factors associated with an increased risk of Parkinson's disease, PD. This study compared diet preferences and oral microbiota profiles in patients with PD vs. healthy controls. This study compared the oral microbiota composition of 59 patients with PD and 108 healthy controls (without neurodegeneration) using 16S rRNA gene amplicon sequencing. According to results, oral microbiota in patients with PD is different compared from healthy controls. In particular, decreased abundance of Proteobacteria, Pastescibacteria, and Tenercutes was observed. The oral cavity of patients with PD was characterized by the high relative abundance of bacteria from the genera

Indexed as

AgedAged, 80 and overCase-Control StudiesCross-Sectional StudiesDiet, WesternFemaleFood PreferencesHumansMaleMicrobiotaMiddle AgedMouthParkinson DiseaseRNA, Ribosomal, 16SRNA, Ribosomal, 16Soral microbiotaParkinson’s diseasethe Western diet

Identifiers

PMID35057536
PMCPMC8778357
OpenAlexW4206310235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.