Evidence map›Paper›PMID 35057428›Full record

Observational studyNutrients2022

Can Overnutrition Lead to Wasting?-The Paradox of Diabetes Mellitus in End-Stage Renal Disease Treated with Maintenance Hemodialysis.

Krzysztof Hoppe, Krzysztof Schwermer, Mikołaj Dopierała, Małgorzata Kałużna, Anna Hoppe, Jadzia Tin-Tsen Chou, Andrzej Oko, Krzysztof Pawlaczyk

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Krzysztof HoppeDepartment of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.ORCID 0000-0002-5123-9228
Krzysztof SchwermerDepartment of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.
Mikołaj DopierałaDepartment of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.
Małgorzata KałużnaDepartment of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.ORCID 0000-0002-2116-4384
Anna HoppeDepartment of Haematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, 60-569 Poznań, Poland.
Jadzia Tin-Tsen ChouDepartment of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.ORCID 0000-0003-4448-8768
Andrzej OkoDepartment of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.
Krzysztof PawlaczykDepartment of Nephrology, Transplantology and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznań, Poland.ORCID 0000-0001-6237-0814
Poznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe population of end-stage renal disease (ESRD) patients with diabetes mellitus (DM) may be at increased risk of protein energy wasting (PEW). The aim of the study was to investigate the impact of DM on selected indicators of PEW in the ESRD population that was undergoing maintenance hemodialysis (MHD).

methodsA total of 515 MHD patients were divided into two subgroups with and without DM. The evaluation of diet composition, Charlson Comorbidity Index (CCI), SGA, and laboratory and BIS analyses were performed. All-cause and cardiovascular mortality was recorded.

resultsDM patients had lower albumin (3.93 (3.61-4.20) vs. 4.10 (3.80-4.30) g/dL,

conclusionsHemodialysis recipients with DM experience overnutrition with a paradoxically higher predisposition to PEW, expressed by a higher SGA score and lower serum markers of nutrition. This population is also more comorbid and is at higher risk of death, including from cardiovascular causes.

Indexed as

Diabetes MellitusRenal DialysisAdipose TissueAgedBiomarkersBody CompositionBody Mass IndexCardiovascular DiseasesCause of DeathCholesterolComorbidityCreatinineDiabetes ComplicationsDiagnostic Self EvaluationDietElectric ImpedanceBiomarkersCholesterolCreatinineSerum Albuminbioelectrical impedance spectroscopy (BIS)body compositiondiabetes mellitus (DM)dietary intakeend-stage renal disease (ESRD)hemodialysis (HD)mortalityobese sarcopeniaprotein energy wasting (PEW)Subjective Global Assessment (SGA)

Identifiers

PMID35057428
PMCPMC8779228
OpenAlexW4206386962

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.