Evidence map›Paper›PMID 35057223›Full record

ReviewMaterials (Basel, Switzerland)2022

Multifunctional Iron Oxide Magnetic Nanoparticles for Biomedical Applications: A Review.

Hung-Vu Tran, Nhat M Ngo, Riddhiman Medhi, Pannaree Srinoi, Tingting Liu, Supparesk Rittikulsittichai, T Randall Lee

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Review
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  12. Article
  13. Fine-Tuning the Superparamagnetic Properties of FeO@FeACS applied materials & interfaces · 2025
    Article
  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hung-Vu TranDepartment of Chemistry and the Texas Center for Superconductivity, University of Houston, 4800 Calhoun Road, Houston, TX 77204-5003, USA.ORCID 0000-0001-8536-2737
Nhat M NgoDepartment of Chemistry and the Texas Center for Superconductivity, University of Houston, 4800 Calhoun Road, Houston, TX 77204-5003, USA.ORCID 0000-0001-5710-1601
Riddhiman MedhiDepartment of Chemistry and the Texas Center for Superconductivity, University of Houston, 4800 Calhoun Road, Houston, TX 77204-5003, USA.ORCID 0000-0002-2368-2468
Pannaree SrinoiDepartment of Chemistry and Centre of Excellence for Innovation in Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.ORCID 0000-0003-4400-468X
Tingting LiuDepartment of Chemistry and the Texas Center for Superconductivity, University of Houston, 4800 Calhoun Road, Houston, TX 77204-5003, USA.
Supparesk RittikulsittichaiDepartment of Chemistry and the Texas Center for Superconductivity, University of Houston, 4800 Calhoun Road, Houston, TX 77204-5003, USA.
T Randall LeeDepartment of Chemistry and the Texas Center for Superconductivity, University of Houston, 4800 Calhoun Road, Houston, TX 77204-5003, USA.ORCID 0000-0001-9584-8861

Funding

United States Air Force Office of Scientific Research AFOSR FA9550-20-1-0349; 20RT0302,Welch Foundation E-1320
6 · The paper itself

Abstract

Due to their good magnetic properties, excellent biocompatibility, and low price, magnetic iron oxide nanoparticles (IONPs) are the most commonly used magnetic nanomaterials and have been extensively explored in biomedical applications. Although magnetic IONPs can be used for a variety of applications in biomedicine, most practical applications require IONP-based platforms that can perform several tasks in parallel. Thus, appropriate engineering and integration of magnetic IONPs with different classes of organic and inorganic materials can produce multifunctional nanoplatforms that can perform several functions simultaneously, allowing their application in a broad spectrum of biomedical fields. This review article summarizes the fabrication of current composite nanoplatforms based on integration of magnetic IONPs with organic dyes, biomolecules (e.g., lipids, DNAs, aptamers, and antibodies), quantum dots, noble metal NPs, and stimuli-responsive polymers. We also highlight the recent technological advances achieved from such integrated multifunctional platforms and their potential use in biomedical applications, including dual-mode imaging for biomolecule detection, targeted drug delivery, photodynamic therapy, chemotherapy, and magnetic hyperthermia therapy.

Indexed as

antibacterialbacterial detectionbiomedical applicationsbiomoleculescancer treatmentdiagnosisdrug deliveryFe3O4fluorescence imagingmagnetic nanoparticlesmagnetic resonance imagingmetal nanoparticlesorganic dyesphotodynamic therapyphotothermal ablationquantum dotsstimuli-responsive polymerssurface functionalizationtumor targeting

Identifiers

PMID35057223
PMCPMC8779542

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.